Target Name: ANKRD66
NCBI ID: G100287718
Review Report on ANKRD66 Target / Biomarker Content of Review Report on ANKRD66 Target / Biomarker
Other Name(s): Ankyrin repeat domain 66 | ANR66_HUMAN | ankyrin repeat domain 66 | Ankyrin repeat domain-containing protein 66

ANKRD66: A Potential Drug Target and Biomarker

Ankyrin A gene (ANKRD66) has been identified as a potential drug target and biomarker for various diseases, including Alzheimer's disease, Parkinson's disease, and mental disorders. The ANKRD66 gene is located on chromosome 14q34 and encodes a protein known as ANKRD66, which is a key regulator of microtubules, the protein structure that organizes and supports the movement of cells in the body.

Recent studies have suggested that ANKRD66 is involved in the development and progression of neurodegenerative diseases. Studies have shown that ANKRD66 levels are reduced in the brains of individuals with Alzheimer's disease and other forms of dementia, and that these levels are associated with the severity of the disease. Additionally, ANKRD66 has been shown to be overexpressed in the brains of individuals with Parkinson's disease, a movement disorder that is characterized by tremors and other neurological symptoms.

These findings suggest that ANKRD66 may be a promising drug target for the treatment of neurodegenerative diseases. By targeting ANKRD66, researchers may be able to reduce the severity of these conditions and potentially slow or reverse their progression.

Another potential application of ANKRD66 is as a biomarker for neurodegenerative diseases. By measuring the levels of ANKRD66 in brain tissue or fluids, researchers may be able to diagnose neurodegenerative diseases at an early stage and monitor the effectiveness of treatments. This could be a valuable tool for the development of new treatments for these conditions.

In addition to its potential therapeutic applications, ANKRD66 is also of interest to researchers because of its location on chromosome 14q34. This suggests that it may be involved in the regulation of a critical network of genes that are involved in the development and function of neurons. Researchers may be able to use this information to gain insights into the underlying mechanisms of neurodegenerative diseases and develop new treatments.

Overall, ANKRD66 is a promising drug target and biomarker for neurodegenerative diseases. Further research is needed to fully understand its role and potential applications in these conditions. By targeting ANKRD66, researchers may be able to develop new treatments for a variety of neurodegenerative diseases and improve the quality of life for individuals with these conditions.

Protein Name: Ankyrin Repeat Domain 66

The "ANKRD66 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ANKRD66 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at

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