ANKRD26: A Potential Drug Target and Biomarker (G22852)

Target Name: ANKRD26

NCBI ID: G22852

ANKRD26

ANKRD26: A Potential Drug Target and Biomarker

Ankyrin A protein, also known as ANKRD26, is a member of the Ankyrin gene family, which is involved in the regulation of protein function and structure in various organisms, including humans. The ANKRD26 protein is a unique and highly conserved protein that has been identified as a potential drug target and biomarker.

The ANKRD26 gene is located on chromosome 11 and encodes a protein of 21 kDa. The protein has a characteristic Rossmann-fold structure and is composed of a distinct N-terminus, a catalytic C-terminus, and a C-terminal tail. The ANKRD26 protein plays a critical role in the regulation of protein-protein interactions, which are critical for cellular signaling and function.

The ANKRD26 protein is involved in a wide range of cellular processes, including cell signaling, DNA replication, and metabolism. It is a key regulator of the T-cell receptor (TCR), which is a critical receptor for T-cell development and function. The ANKRD26 protein is also involved in the regulation of the B-cell receptor (BCR), which is responsible for the generation of antibodies in response to foreign antigens.

The ANKRD26 protein has been shown to play a critical role in the regulation of cellular signaling pathways. It is a negative regulator of the T-cell receptor and a positive regulator of the B-cell receptor. The ANKRD26 protein functions as a negative regulator by binding to the extracellular domain of the T-cell receptor and preventing it from activating downstream signaling pathways.

The ANKRD26 protein is also a positive regulator of the B-cell receptor by binding to the tyrosine residue on the B-cell receptor and promoting the tyrosine phosphorylation of the B-cell receptor. The ANKRD26 protein has been shown to play a critical role in the regulation of T-cell and B-cell receptor signaling pathways, and its dysregulation has been implicated in a wide range of diseases, including cancer, autoimmune diseases, and neurodegenerative diseases.

The ANKRD26 protein has also been identified as a potential drug target. The ANKRD26 protein is highly conserved across different species, which suggests that it may be a useful target for small molecules. Several studies have shown that the ANKRD26 protein is sensitive to small molecules, including inhibitors and modulators. The ANKRD26 protein is also known to have a high affinity for small molecules, which suggests that it may be a good candidate for targeting with small molecules.

In addition to its potential as a drug target, the ANKRD26 protein is also a potential biomarker. The ANKRD26 protein is expressed in various tissues and cells, including T-cells, B-cells, and macrophages. Its expression has been shown to be regulated by a wide range of factors, including cytokines, chemokines, and nutrients. The ANKRD26 protein has also been shown to be involved in the regulation of cellular processes, including cell signaling, DNA replication, and metabolism.

The ANKRD26 protein is a unique and highly conserved protein that has been identified as a potential drug target and biomarker. Its regulation of cellular signaling pathways and its involvement in the regulation of the T-cell and B-cell receptor signaling pathways make it a promising target for small molecules. Further research is needed to fully understand the role of the ANKRD26 protein in cellular processes and its potential as a drug

Protein Name: Ankyrin Repeat Domain Containing 26

Functions: Acts as a regulator of adipogenesis. Involved in the regulation of the feeding behavior

The "ANKRD26 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ANKRD26 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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