Target Name: PROS1
NCBI ID: G5627
Review Report on PROS1 Target / Biomarker Content of Review Report on PROS1 Target / Biomarker
PROS1
Other Name(s): THPH6 | PROS1 variant 2 | PS22 | vitamin K-dependent plasma protein S | Preproprotein S | THPH5 | Vitamin K-dependent protein S | PSA | Protein S | PS24 | Vitamin K-dependent protein S (isoform 1) | PS25 | PROS_HUMAN | Protein S, transcript variant 1 | PS23 | Vitamin K-dependent protein S (isoform 2) | Protein S, transcript variant 2 | protein S (alpha) | PROS1 variant 1 | PS21 | protein Sa | protein S | Protein S (alpha) | PROS

PROS1: Regulating Protein Homeostasis and Cellular Processes

PROS1 (Prolyl hydroxylase 1) is a gene that encodes a protein involved in the regulation of protein homeostasis in the body. The protein produced by this gene has been shown to play a role in the development and progression of various diseases, including cancer. As As a result, PROS1 has become a focus of interest for researchers studying the mechanisms underlying these diseases and for the development of new treatments.

One of the key functions of PROS1 is its role in regulating the levels of protein in the body. This is important for maintaining the proper structure and function of the proteins that make up the body's cells and tissues. When the levels of a protein become too high or too low, it can cause a variety of problems, including the development of diseases.

Research has shown that PROS1 plays a key role in the regulation of the level of a protein called Tmem1, which is involved in cell signaling. Tmem1 levels are regulated by PROS1, and studies have suggested that changes in PROS1 activity may contribute to the development of certain diseases.

Another function of PROS1 is its role in the regulation of protein stability. This is important for maintaining the stability of proteins and for preventing their breakdown or misfolding. Disruptions in protein stability have been linked to a variety of diseases, including cancer.

Research has also shown that PROS1 plays a role in the regulation of cellular processes such as cell division and apoptosis. Prolyl hydroxylase 1 has been shown to play a key role in the regulation of the level of a protein called p21, which is involved in the Transcription of cell division cycle checkpoint genes.

In addition to its role in regulating protein levels and stability, PROS1 has also been shown to play a role in the regulation of gene expression. This is important for the development and progression of diseases, as changes in gene expression can contribute to the development of certain diseases.

Overall, PROS1 is a gene that has important functions in the regulation of protein homeostasis and cellular processes. Its potential as a drug target or biomarker makes it an attractive target for researchers studying the mechanisms underlying various diseases. Further research is needed to fully understand the role of PROS1 in disease development and to develop new treatments.

Protein Name: Protein S

Functions: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis

The "PROS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PROS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PROS2P | PROSER1 | PROSER2 | PROSER2-AS1 | PROSER3 | Prostaglandin EP Receptor | Prostaglandin synthase | Prostanoid Receptor | Prostanoid TP receptor | Proteasome 20S | Proteasome 26S | Proteasome Complex | Protein arginine N-methyltransferase | Protein disulfide-isomerase | Protein farnesyltransferase | Protein geranylgeranyltransferase type II | Protein kinase C | Protein Kinase D (PKD) | Protein kinase N | Protein NDRG2 (isoform a) | Protein Phosphatase | Protein Phosphatase 2A | Protein Phosphatase 2B | Protein phosphatase 6 | Protein phosphatase-1 | Protein transport protein Sec61 complex | Protein Tyrosine Phosphatase (PTP) | Protein Tyrosine Phosphatase Type IVA | Protein-Synthesizing GTPase (Elongation Factor) | Protocadherin | PROX1 | PROX1-AS1 | PROX2 | PROZ | PRPF18 | PRPF19 | PRPF3 | PRPF31 | PRPF38A | PRPF38B | PRPF39 | PRPF4 | PRPF40A | PRPF40B | PRPF4B | PRPF6 | PRPF8 | PRPH | PRPH2 | PRPS1 | PRPS1L1 | PRPS2 | PRPSAP1 | PRPSAP2 | PRR11 | PRR12 | PRR13 | PRR13P1 | PRR13P3 | PRR14 | PRR14L | PRR15 | PRR15L | PRR16 | PRR18 | PRR19 | PRR20B | PRR20C | PRR20D | PRR21 | PRR22 | PRR23A | PRR23B | PRR23C | PRR23D1 | PRR23E | PRR25 | PRR27 | PRR29 | PRR3 | PRR30 | PRR32 | PRR34 | PRR34-AS1 | PRR35 | PRR36 | PRR4 | PRR5 | PRR5-ARHGAP8 | PRR5L | PRR7 | PRR7-AS1 | PRR9 | PRRC1 | PRRC2A | PRRC2B | PRRC2C | PRRG1 | PRRG2 | PRRG3