Target Name: PRPF4
NCBI ID: G9128
Review Report on PRPF4 Target / Biomarker Content of Review Report on PRPF4 Target / Biomarker
PRPF4
Other Name(s): U4/U6 small nuclear ribonucleoprotein Prp4 | PRP4_HUMAN | PRP4 | HPRP4P | PRP4 pre-mRNA processing factor 4 homolog | Prp4p | PRP4 homolog | pre-mRNA processing factor 4 | hPrp4 | WD splicing factor Prp4 | U4/U6 small nuclear ribonucleoprotein Prp4 (isoform 1) | PRP4/STK/WD splicing factor | PRPF4 variant 1 | OTTHUMP00000021946 | Pre-mRNA processing factor 4, transcript variant 1 | RP70 | U4/U6 snRNP 60 kDa protein | OTTHUMP00000021947 | HPRP4 | SNRNP60

PRPF4: A Potential Drug Target Or Biomarker

PRPF4, also known as U4/U6 small nuclear ribonucleoprotein Prp4, is a protein that is expressed in most tissues of the body. It plays a critical role in the regulation of DNA replication, repair, and other cellular processes. The protein is composed of two subunits, Prp4 and Prp6, which are held together by a disulfide bond.

Recent studies have suggested that PRPF4 may have potential as a drug target or biomarker. One potential mechanism by which PRPF4 could be targeted by drugs is through its role in DNA replication and repair. PRPF4 is a key component of the replication machinery, which is responsible for copying the genetic material from the DNA template to the new RNA template during the process of DNA replication.

Studies have shown that alterations in PRPF4 levels or activity have been associated with various cellular processes, including cancer, neurodegenerative diseases, and developmental disorders. For example, several studies have shown that increased levels of PRPF4 have been observed in various types of cancer, such as breast, ovarian, and prostate cancer.

Additionally, PRPF4 has also been shown to be involved in the regulation of cellular processes that are important for brain development and function, such as the production of neurotransmitters and the regulation of synaptic plasticity. This suggests that alterations in PRPF4 levels or activity may be involved in the development or progression of certain neurological disorders.

Another potential mechanism by which PRPF4 could be used as a biomarker is its role in the regulation of cellular processes that are important for overall cellular health and longevity. PRPF4 has been shown to play a role in regulating cellular processes that are important for DNA repair, DNA replication, and apoptosis, among others.

Studies have shown that alterations in PRPF4 levels or activity have been associated with various cellular processes that are important for overall cellular health and longevity, such as the regulation of cellular stress and the production of cellular waste products. These alterations have been linked to the development of various diseases, including neurodegenerative disorders, cancer, and cardiovascular disease.

In conclusion, PRPF4 is a protein that is expressed in most tissues of the body and plays a critical role in the regulation of DNA replication, repair, and other cellular processes. Recent studies have suggested that PRPF4 may have potential as a drug target or biomarker, due to its involvement in various cellular processes that are important for overall cellular health and longevity. Further research is needed to fully understand the role of PRPF4 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Pre-mRNA Processing Factor 4

Functions: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex)

The "PRPF4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRPF4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PRPF40A | PRPF40B | PRPF4B | PRPF6 | PRPF8 | PRPH | PRPH2 | PRPS1 | PRPS1L1 | PRPS2 | PRPSAP1 | PRPSAP2 | PRR11 | PRR12 | PRR13 | PRR13P1 | PRR13P3 | PRR14 | PRR14L | PRR15 | PRR15L | PRR16 | PRR18 | PRR19 | PRR20B | PRR20C | PRR20D | PRR21 | PRR22 | PRR23A | PRR23B | PRR23C | PRR23D1 | PRR23E | PRR25 | PRR27 | PRR29 | PRR3 | PRR30 | PRR32 | PRR34 | PRR34-AS1 | PRR35 | PRR36 | PRR4 | PRR5 | PRR5-ARHGAP8 | PRR5L | PRR7 | PRR7-AS1 | PRR9 | PRRC1 | PRRC2A | PRRC2B | PRRC2C | PRRG1 | PRRG2 | PRRG3 | PRRG4 | PRRT1 | PRRT2 | PRRT3 | PRRT3-AS1 | PRRT4 | PRRX1 | PRRX2 | PRSS1 | PRSS12 | PRSS16 | PRSS2 | PRSS21 | PRSS22 | PRSS23 | PRSS27 | PRSS3 | PRSS30P | PRSS33 | PRSS35 | PRSS36 | PRSS37 | PRSS38 | PRSS3P1 | PRSS3P2 | PRSS3P3 | PRSS40A | PRSS41 | PRSS42P | PRSS45P | PRSS46P | PRSS48 | PRSS50 | PRSS53 | PRSS54 | PRSS55 | PRSS56 | PRSS57 | PRSS58 | PRSS59P | PRSS8 | PRTFDC1