Target Name: PRR13
NCBI ID: G54458
Review Report on PRR13 Target / Biomarker Content of Review Report on PRR13 Target / Biomarker
PRR13
Other Name(s): PRR13_HUMAN | Taxane-resistance protein | proline rich 13 | Proline rich 13, transcript variant 2 | PRR13 variant 2 | Proline-rich protein 13 (isoform 1) | taxane-resistance protein | DKFZp564J157 | FLJ23818 | TXR1 | Proline-rich protein 13

PRR13: A Potential Drug Target and Biomarker

PRR13 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its full name is prion-repeat region 13, and it is a unique protein that is found in the brain. PRR13 is known for its role in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Recent studies have suggested that PRR13 may be a drug target, and that it may be able to be used to treat these debilitating diseases. This is because PRR13 is involved in the formation of beta-amyloid plaques, which are a hallmark of neurodegenerative diseases. Beta-amyloid plaques are composed of abnormal aggregates of the protein beta-amyloid, which can cause the formation of neurofibrillary tangles and the disruption of normal brain cells.

In addition to its role in the formation of beta-amyloid plaques, PRR13 has also been shown to be involved in the regulation of normal brain function. Studies have shown that PRR13 is involved in the formation of glial cells, which are responsible for the support and maintenance of nerve cells. Additionally, PRR13 is involved in the regulation of the immune response, which is important for the defense against neurodegenerative diseases.

Given the potential role of PRR13 in the development and progression of neurodegenerative diseases, researchers are actively searching for drugs that can inhibit its activity. This is because once these drugs can be developed and tested, they may be used to treat a wide range of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and other forms of dementia.

In conclusion, PRR13 is a protein that is expressed in various tissues of the body and is involved in the formation of beta-amyloid plaques, which are a hallmark of neurodegenerative diseases. Its potential as a drug target makes it an attractive target for researchers to investigate, and once drugs can be developed and tested, they may be used to treat a wide range of neurodegenerative diseases.

Protein Name: Proline Rich 13

Functions: Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane-induced apoptosis

The "PRR13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRR13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PRR13P1 | PRR13P3 | PRR14 | PRR14L | PRR15 | PRR15L | PRR16 | PRR18 | PRR19 | PRR20B | PRR20C | PRR20D | PRR21 | PRR22 | PRR23A | PRR23B | PRR23C | PRR23D1 | PRR23E | PRR25 | PRR27 | PRR29 | PRR3 | PRR30 | PRR32 | PRR34 | PRR34-AS1 | PRR35 | PRR36 | PRR4 | PRR5 | PRR5-ARHGAP8 | PRR5L | PRR7 | PRR7-AS1 | PRR9 | PRRC1 | PRRC2A | PRRC2B | PRRC2C | PRRG1 | PRRG2 | PRRG3 | PRRG4 | PRRT1 | PRRT2 | PRRT3 | PRRT3-AS1 | PRRT4 | PRRX1 | PRRX2 | PRSS1 | PRSS12 | PRSS16 | PRSS2 | PRSS21 | PRSS22 | PRSS23 | PRSS27 | PRSS3 | PRSS30P | PRSS33 | PRSS35 | PRSS36 | PRSS37 | PRSS38 | PRSS3P1 | PRSS3P2 | PRSS3P3 | PRSS40A | PRSS41 | PRSS42P | PRSS45P | PRSS46P | PRSS48 | PRSS50 | PRSS53 | PRSS54 | PRSS55 | PRSS56 | PRSS57 | PRSS58 | PRSS59P | PRSS8 | PRTFDC1 | PRTG | PRTN3 | PRUNE1 | PRUNE2 | PRX | PRXL2A | PRXL2B | PRXL2C | PRY | PRY2 | PRYP3 | PRYP4 | PSAP | PSAPL1 | PSAT1