Target Name: PRR7
NCBI ID: G80758
Review Report on PRR7 Target / Biomarker Content of Review Report on PRR7 Target / Biomarker
PRR7
Other Name(s): Proline rich 7, synaptic, transcript variant 1 | PRR7_HUMAN | Synaptic proline-rich membrane protein | Proline-rich protein 7 | ZTNF13 | MGC10772 | proline rich 7, synaptic | synaptic proline-rich membrane protein | PRR7 variant 1

PRR7: A Potential Drug Target and Biomarker

Proline-rich protein 7 (PRR7) is a gene that has been identified as a potential drug target and biomarker for various diseases, including neurodegenerative disorders, psychiatric illnesses, and cancer. PRR7 is a protein that is expressed in the brain and is involved in the regulation of essential cellular processes, including cell signaling, neurotransmitter release, and synaptic plasticity.

The discovery of PRR7 as a potential drug target and biomarker has significant implications for the development of new treatments for a variety of diseases. PRR7 is a promising target for small molecule inhibitors, which can be used to treat a wide range of disorders, including neurodegenerative disorders, psychiatric illnesses, and cancer.

One of the key challenges in developing new treatments for PRR7-related disorders is the identification of effective inhibitors. PRR7 is involved in many cellular processes that are essential for brain function, so it is important to carefully design inhibitors that do not have unintended consequences. This will require a combination of techniques, including high-throughput screening and structural bioinformatics analysis, to identify effective inhibitors.

Another approach to identifying potential drug targets and biomarkers for PRR7 is to use computational tools to predict the binding of small molecules to the protein. This can help identify potential inhibitors that are likely to be effective. This approach is being developed by a team of researchers at the University of California, San Diego, and will be an important tool for identifying new treatments for PRR7-related disorders.

Once effective inhibitors have been identified, they can be tested for effectiveness in animal models of the disease. This will help determine if the inhibitors are effective in treating the disease and could be used in humans. If the inhibitors are effective in animal models, they can be tested in human clinical trials to determine their safety and effectiveness.

PRR7 is also being studied as a potential biomarker for various diseases, including neurodegenerative disorders, psychiatric illnesses, and cancer. By measuring the level of PRR7 in brain tissue, researchers can monitor the effectiveness of treatments and track the progression of the disease. This can be an important tool for the development of new treatments for PRR7-related disorders.

In conclusion, PRR7 is a promising protein that can be used as a drug target and biomarker for various diseases. The development of effective inhibitors and biomarkers for PRR7 will require a combination of techniques, including high-throughput screening, computational tools, and animal testing. Once effective treatments have been identified, they can be tested in human clinical trials to determine their safety and effectiveness.

Protein Name: Proline Rich 7, Synaptic

Functions: Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (PubMed:27458189). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:21460222). Might promote apoptosis in T cells (PubMed:21460222)

The "PRR7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRR7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PRR7-AS1 | PRR9 | PRRC1 | PRRC2A | PRRC2B | PRRC2C | PRRG1 | PRRG2 | PRRG3 | PRRG4 | PRRT1 | PRRT2 | PRRT3 | PRRT3-AS1 | PRRT4 | PRRX1 | PRRX2 | PRSS1 | PRSS12 | PRSS16 | PRSS2 | PRSS21 | PRSS22 | PRSS23 | PRSS27 | PRSS3 | PRSS30P | PRSS33 | PRSS35 | PRSS36 | PRSS37 | PRSS38 | PRSS3P1 | PRSS3P2 | PRSS3P3 | PRSS40A | PRSS41 | PRSS42P | PRSS45P | PRSS46P | PRSS48 | PRSS50 | PRSS53 | PRSS54 | PRSS55 | PRSS56 | PRSS57 | PRSS58 | PRSS59P | PRSS8 | PRTFDC1 | PRTG | PRTN3 | PRUNE1 | PRUNE2 | PRX | PRXL2A | PRXL2B | PRXL2C | PRY | PRY2 | PRYP3 | PRYP4 | PSAP | PSAPL1 | PSAT1 | PSAT1P1 | PSAT1P3 | PSCA | PSD | PSD2 | PSD3 | PSD4 | PSEN1 | PSEN2 | PSENEN | PSG1 | PSG10P | PSG11 | PSG2 | PSG3 | PSG4 | PSG5 | PSG6 | PSG7 | PSG8 | PSG9 | PSIP1 | PSKH1 | PSKH2 | PSMA1 | PSMA2 | PSMA3 | PSMA3-AS1 | PSMA3P1 | PSMA4 | PSMA5 | PSMA6 | PSMA7 | PSMA8