PRR5L: A Potential Drug Target and Biomarker (G79899)

Target Name: PRR5L

NCBI ID: G79899

PRR5L

PRR5L: A Potential Drug Target and Biomarker

PRR5L, short for pr5L gene, is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and recent studies have shed light on its potential as a drug vector.

The pr5L gene is located on chromosome 19 and has been shown to play a role in regulating gene expression in various cellular processes. It has been shown to regulate the expression of genes involved in cell adhesion, migration, and invasion, which are crucial processes for the development and progression of many diseases.

One of the reasons why PRR5L has generated so much interest is its potential as a drug target is its unique structure. Unlike many proteins, which have a well-defined amino acid sequence, PRR5L is a non-coding RNA molecule. This means that its function is not determined by the sequence of its amino acids, but rather by its three-dimensional structure and interactions with other molecules.

The structure of PRR5L has been studied in great detail, and it has been shown to have a unique fusiform structure. This structure is composed of a long stem region that ends in a hexonucleotide loop, a middle region that has a hinge-like shape, and a short tail region that is involved in its interactions with other molecules.

The hinge-like shape of PRR5L's middle region is particularly noteworthy, as it is known to play a key role in the regulation of cellular processes that are critical for disease development. This region has been shown to interact with a variety of protein molecules, including Niannianfeng, KAPK3 and PKC5, etc. These protein molecules play important roles in cell signaling, cell adhesion and cell migration.

Additionally, PRR5L has been shown to play a role in the regulation of stem cell proliferation and self-renewal. This has important implications for the development of cancer, as cancer stem cells are highly resistant to chemotherapy and have a high ability to regenerate.

PRR5L has also been shown to be involved in the regulation of tissue repair and regeneration. This is yet another potential drug target for PRR5L, as many diseases, including cancer, are characterized by tissue damage and regeneration disorders.

In addition to its potential as a drug target, PRR5L also has the potential as a biomarker. Its unique structure and function make it an attractive target for researchers to investigate the role of RNA in disease, including the regulation of gene expression and cellular processes.

Several studies have shown that PRR5L is involved in the regulation of various cellular processes, including cell adhesion, migration, and invasion. This suggests that PRR5L may be a useful biomarker for the diagnosis and treatment of diseases characterized by these processes, such as cancer and neurodegenerative diseases.

Another promising aspect of PRR5L is its potential as a drug vector. The use of RNA-based drugs, such as RNA interference (RNAi) drugs, has become a popular method for treating diseases caused by misregulated gene expression. PRR5L offers a unique advantage as a drug vector, as its structure and function are well-studied, making it easier to design and optimize RNAi drugs.

In conclusion, PRR5L is a non-coding RNA molecule that has generated a lot of interest due to its unique structure and function. Its potential as a drug target and biomarker makes it an attractive target for researchers to investigate the role of RNA in disease. Further studies are needed to fully understand its potential as a drug vector and to develop effective therapies based on it.

Protein Name: Proline Rich 5 Like

Functions: Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton (PubMed:17461779). Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration (PubMed:22609986). Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress (PubMed:21964062). Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress (PubMed:21964062)

The "PRR5L Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRR5L comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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