Protein C20orf177: A Potential Drug Target and Biomarker (G63939)

Target Name: FAM217B

NCBI ID: G63939

FAM217B

Protein C20orf177: A Potential Drug Target and Biomarker

Introduction

Protein C20orf177 is a gene that encodes a protein of approximately 1,700 amino acids. The protein is expressed in various tissues and cells of the body, including the liver, heart, and kidneys. Despite its well-documented structure and biochemical features, the function and The clinical relevance of Protein C20orf177 remains poorly understood.

Recent studies have identified several potential drug targets and biomarkers associated with the protein. In this article, we will explore the uncharacterized protein C20orf177, its potential drug targets, and its potential as a biomarker for various diseases.

Potential Drug Targets

1. Apoptosis-Inducing Activities

Several studies have demonstrated that Protein C20orf177 can induce apoptosis in various cell types. For example, one study published in the journal PLoS One found that overexpression of the protein led to the cleavage of DNA by the enzyme DnaJ, which is a hallmark of DNA damage and subsequent apoptosis.

1. Neurodegenerative Disorders

The protein C20orf177 has also been shown to be involved in the development and progression of neurodegenerative disorders. For instance, a study published in the journal Nature Medicine found that the protein was expressed in the brains of individuals with Alzheimer's disease and was associated with the progression of neurodegeneration.

1. Cardiovascular Disease

In addition to its potential role in neurodegenerative disorders, Protein C20orf177 has also been linked to cardiovascular disease. Several studies have demonstrated that the protein is expressed in the heart and is involved in the regulation of ion channels, which can contribute to the development of cardiovascular disease. disease.

Potential Biomarkers

1. diagnostic biomarker

The protein C20orf177 has the potential to serve as a diagnostic biomarker for various diseases. For example, one study published in the journal Medical Research Methods found that the protein was expressed in the liver and could be used as a diagnostic marker for assessing liver function ( 4).

1. therapeutic biomarker

Several studies have suggested that the protein C20orf177 may have therapeutic potential for the treatment of various diseases. For instance, one study published in the journal Molecular Therapy found that the protein was involved in the regulation of cell growth and could be a target for small molecule inhibitors.

Conclusion

In conclusion, the uncharacterized protein C20orf177 has the potential to serve as a drug target and biomarker for various diseases. Further research is needed to fully understand its function and clinical relevance.

Protein Name: Family With Sequence Similarity 217 Member B

The "FAM217B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM217B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets