Target Name: LIPK
NCBI ID: G643414
Review Report on LIPK Target / Biomarker Content of Review Report on LIPK Target / Biomarker
LIPK
Other Name(s): Lipase-like, ab-hydrolase domain containing 2 | Lipase-like abhydrolase domain-containing protein 2 | Lipase K | lipase K | lipase-like abhydrolase domain-containing protein 2 | lipase-like, ab-hydrolase domain containing 2 | bA186O14.2 | lipase family member K | LIPK variant 1 | Lipase member K | LIPL2 | LIPK_HUMAN | Lipase member K (isoform 1) | Lipase family member K, transcript variant 1

Lipase-like AB-Hydrolase Domain Containing 2 (LIPK): Potential Drug Target Or Biomarker

Lipase-like, ab-hydrolase domain containing 2 (LIPK) is a protein that is expressed in various tissues and cells in the human body. It is a member of the Lipase-like Superfamily 1 and has been identified as a potential drug target or biomarker.

LIPK is a 21-kDa protein that is localized to the endoplasmic reticulum (ER) and is involved in various cellular processes, including metabolism, inflammation, and stress. It is a key regulator of lipid metabolism and has been shown to play a role in the regulation of cellular signaling pathways, such as the TGF-β pathway.

One of the key functions of LIPK is its ability to catalyze the hydrolysis of lipids, which is critical for the production of energy and the maintenance of cellular membrane structure. LIPK is also involved in the regulation of lipid metabolism and has been shown to play a role in the treatment of various metabolic disorders, such as obesity and type 2 diabetes.

In addition to its role in lipid metabolism, LIPK is also involved in the regulation of cellular signaling pathways. It is a key regulator of the TGF-β pathway, which is involved in cell growth, differentiation, and inflammation. LIPK has also been shown to play a role in the regulation of cell proliferation and has been shown to be involved in the development of various types of cancer.

LIPK is also involved in the regulation of cellular stress responses. It has been shown to play a role in the regulation of cellular stress responses, including the production of reactive oxygen species (ROS) and the production of inflammatory cytokines. This may have important implications for the development of diseases that are characterized by cellular stress, such as neurodegenerative diseases and chronic inflammatory diseases.

In conclusion, LIPK is a protein that is expressed in various tissues and cells in the human body and is involved in various cellular processes, including metabolism, inflammation, and stress. It is a key regulator of lipid metabolism and has been shown to play a role in the regulation of cellular signaling pathways, including the TGF-β pathway. LIPK may also be a potential drug target or biomarker for the development of various diseases. Further research is needed to fully understand the role of LIPK in cellular processes and its potential as a drug target or biomarker.

Protein Name: Lipase Family Member K

Functions: Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers

The "LIPK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LIPK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LIPM | LIPN | Lipoxygenase | Liprin-beta-1-like | LIPT1 | LIPT2 | LIPT2-AS1 | LITAF | Liver Bile Transporters (LBAT) | LIX1 | LIX1-AS1 | LIX1L | LKAAEAR1 | LKB1-LIP1-SMAD4 complex | LL22NC03-63E9.3 | LLCFC1 | LLGL1 | LLGL2 | LLPH | LMAN1 | LMAN1L | LMAN2 | LMAN2L | LMBR1 | LMBR1L | LMBRD1 | LMBRD2 | LMCD1 | LMCD1-AS1 | LMF1 | LMF2 | LMLN | LMNA | LMNB1 | LMNB2 | LMNTD1 | LMNTD2 | LMNTD2-AS1 | LMO1 | LMO2 | LMO3 | LMO4 | LMO7 | LMO7-AS1 | LMO7DN | LMOD1 | LMOD2 | LMOD3 | LMTK2 | LMTK3 | LMX1A | LMX1B | LMX1B-DT | LNC-LBCS | LNCAROD | LNCARSR | LNCATV | LNCNEF | LNCOC1 | LNCOG | LNCPRESS1 | LNCRI | LNCRNA-ATB | LNCRNA-IUR | LNCTAM34A | LNP1 | LNPEP | LNPK | LNX1 | LNX1-AS1 | LNX2 | LOC100127946 | LOC100127955 | LOC100128002 | LOC100128028 | LOC100128050 | LOC100128059 | LOC100128079 | LOC100128093 | LOC100128164 | LOC100128242 | LOC100128288 | LOC100128317 | LOC100128361 | LOC100128398 | LOC100128494 | LOC100128593 | LOC100128770 | LOC100128966 | LOC100128988 | LOC100129034 | LOC100129098 | LOC100129148 | LOC100129175 | LOC100129203 | LOC100129215 | LOC100129316 | LOC100129381 | LOC100129434 | LOC100129455