FABP12: A promising drug target and biomarker for fatty acid binding protein 12

Target Name: FABP12

NCBI ID: G646486

FABP12

FABP12: A promising drug target and biomarker for fatty acid binding protein 12

Abstract:

Fatty acid binding protein 12 (FABP12) is a protein that plays a crucial role in the regulation of lipid metabolism, and is considered as a potential drug target and biomarker. Obesity and metabolic disorders are major health issues, and FABP12 has been identified as a promising target for intervention. This article will provide an overview of FABP12, its functions, and potential as a drug target and biomarker.

Introduction:

Fatty acid binding protein 12 (FABP12) is a member of the fatty acid binding protein (FABP) family, which includes 11 other proteins that play a crucial role in the regulation of lipid metabolism. These proteins have been identified as potential drug targets and biomarkers for various metabolic disorders, including obesity, diabetes, and cardiovascular diseases.

FABP12 is a 12-kDa protein that is expressed in various tissues and cells, including liver, muscle, and fat cells. It is characterized by a N-terminus that contains a unique farnesylated cysteine 鈥嬧?媟esidue, which is important for its stability and functions. FABP12 also has a C-terminus that contains a glycine residue, which is important for its interactions with other proteins.

FABP12 functions:

FABP12 is involved in the regulation of various lipid metabolic pathways, including the synthesis, metabolism, and storage of fatty acids. It plays a crucial role in the regulation of triacylglycerol (TAG) synthesis, which is a key step in the metabolism of fatty acids.

FABP12 has been shown to interact with various nuclear and cytoplasmic proteins, including transcription factors, metabolic enzymes, and signaling molecules. It has been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

FABP12 has also been shown to be involved in the regulation of various signaling pathways, including the TGF-β pathway, which is involved in cell growth and metabolism. It has been shown to play a role in the regulation of the activities of several transcription factors , including FASN, LXR, and nuclear factor of activating transcription (NFAT).

FABP12 potential as a drug target:

FABP12 has been identified as a potential drug target for various metabolic disorders, including obesity, diabetes, and cardiovascular diseases. The obesity and cardiovascular diseases are major health issues that are associated with an increased risk of various cardiovascular events, including heart failure, hypertension, and stroke.

FABP12 has been shown to play a role in the regulation of cellular processes that are associated with obesity and cardiovascular disease, such as the regulation of lipid metabolism and cellular signaling pathways. It has been shown to interact with several proteins that are involved in the regulation of obesity and cardiovascular disease, including transcription factors, metabolic enzymes, and signaling molecules.

FABP12 has also been shown to be involved in the regulation of cellular processes that are associated with diabetes, such as the regulation of insulin sensitivity and glucose metabolism. It has been shown to interact with several proteins that are involved in the regulation of diabetes, including transcription factors, metabolic enzymes, and signaling molecules.

FABP12 potential as a biomarker:

FABP12 has also been identified as a potential biomarker for various metabolic disorders, including obesity, diabetes, and cardiovascular diseases. The development of new biomarkers for obesity and cardiovascular diseases is a major focus of research in the field of metabol

Protein Name: Fatty Acid Binding Protein 12

Functions: May play a role in lipid transport

The "FABP12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FABP12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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