Target Name: MIR4433A
NCBI ID: G100616265
Review Report on MIR4433A Target / Biomarker Content of Review Report on MIR4433A Target / Biomarker
MIR4433A
Other Name(s): MicroRNA 4433a | hsa-mir-4433a | hsa-miR-4433a-3p | microRNA 4433a | MIR4433 | hsa-miR-4433a-5p

MIR4433A: A Potential Drug Target and Biomarker

MIR4433A, a gene encoding for a protein known as MIR4433A, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.

The MIR4433A protein is a member of the heat shock protein (HSP) family, which are known to play a crucial role in the regulation of protein expression and stability in cells under stress conditions. HSPs are highly conserved across various species, and they have been implicated in a wide range of cellular processes, including stress response, DNA repair, and cell signaling.

MIR4433A is unique among HSPs due to its highly acidic amino acid residues at its C-terminus. These residues have been shown to interact with various molecules in the cell, including transcription factors, thereby influencing the expression of genes involved in stress response, DNA repair, and cell signaling.

Several studies have demonstrated that MIR4433A is involved in various cellular processes that are crucial for human health and disease. For example, MIR4433A has been shown to play a role in stress response, as it is highly expressed in genes involved in the cellular stress response pathway. Additionally, MIR4433A has been linked to the development and progression of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

MIR4433A has also been shown to be involved in the regulation of cell signaling pathways that are involved in cancer progression. For instance, MIR4433A has been shown to interact with the protein PD-L1, which is a negative regulator of the T-cell receptor signaling pathway. The combination of MIR4433A and PD-L1 has led to the regulation of T-cell proliferation and the suppression of cancer cell growth.

Furthermore, MIR4433A has also been shown to be involved in the regulation of inflammation, which is a major contributor to various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. MIR4433A has been shown to interact with various cytokines and immune cell surface molecules, including NF-kappa-B and T-cell receptor signaling pathways.

In conclusion, MIR4433A is a highly conserved and unique protein that has the potential to serve as a drug target and biomarker for various diseases. Its involvement in various cellular processes, including stress response, neurodegenerative disorders, cancer, and inflammation make it an attractive target for researchers to study and develop new treatments. Further research is needed to fully understand the role of MIR4433A in human health and disease, and to explore its potential as a drug and biomarker.

Protein Name: MicroRNA 4433a

The "MIR4433A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR4433A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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