Target Name: C1orf21
NCBI ID: G81563
Review Report on C1orf21 Target / Biomarker Content of Review Report on C1orf21 Target / Biomarker
C1orf21
Other Name(s): chromosome 1 open reading frame 21 | Chromosome 1 open reading frame 21 | CA021_HUMAN | cell proliferation-inducing gene 13 protein | PIG13 | Uncharacterized protein C1orf21 | proliferation-inducing protein 13 | Cell proliferation-inducing gene 13 protein | Proliferation-inducing protein 13

C1orf21: A Potential Drug Target for Various Diseases

C1orf21, also known as chromosome 1 open reading frame 21, is a gene that has been identified as a potential drug target or biomarker for various diseases. Its unique genetic makeup has led to a growing interest in its potential for therapeutic intervention.

C1orf21 is located on chromosome 1, which is one of the most commonly chromosomes in the human body. It is a gene that encodes a protein known as CRM1, which is a critical regulator of cell division and growth. The C1orf21 gene has been shown to be mutated in various diseases, including cancer, neurodegenerative diseases, and developmental disorders.

One of the most significant aspects of the C1orf21 gene is its role in cancer. Many studies have shown that CRIM-1, the gene encoding CRM1, is often mutated in various types of cancer. The most common type of cancer that is associated with CRIM-1 is lung cancer. Studies have shown that individuals with mutations in the C1orf21 gene are more likely to develop lung cancer, and that these mutations can lead to the development of more aggressive and treatment-resistant tumors.

Another potential drug target associated with C1orf21 is its role in neurodegenerative diseases. Many of these diseases, such as Alzheimer's and Parkinson's, are characterized by the progressive loss of brain cells that are responsible for maintaining cognitive function. The C1orf21 gene has been shown to be involved in the development and progression of these diseases. Studies have shown that individuals with mutations in the C1orf21 gene are more likely to develop neurodegenerative diseases, and that these mutations can contribute to the severity and progression of these conditions.

In addition to its potential as a drug target or biomarker, C1orf21 has also been shown to be involved in the development of other diseases. For example, studies have shown that individuals with mutations in the C1orf21 gene are more likely to develop systemic lupus erythematosus, an autoimmune disease that can affect multiple organs and systems in the body.

The potential therapeutic applications of C1orf21 are vast and continue to be explored by researchers. For example, researchers are currently studying the potential benefits of targeting CRIM-1 directly with drugs to treat cancer and neurodegenerative diseases. Additionally, researchers are also studying the potential benefits of blocking the activity of CRIM-1 to prevent the development of neurodegenerative diseases.

In conclusion, C1orf21 is a gene that has been identified as a potential drug target or biomarker for various diseases. Its unique genetic makeup and its involvement in the development and progression of cancer, neurodegenerative diseases, and other conditions make it an attractive target for therapeutic intervention. As research continues to progress, the potential therapeutic applications of C1orf21 will continue to emerge, and the importance of this gene in understanding and combating various diseases will continue to be recognized.

Protein Name: Chromosome 1 Open Reading Frame 21

The "C1orf21 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C1orf21 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

C1orf210 | C1orf216 | C1orf220 | C1orf226 | C1orf35 | C1orf43 | C1orf50 | C1orf52 | C1orf53 | C1orf54 | C1orf56 | C1orf68 | C1orf74 | C1orf87 | C1orf94 | C1QA | C1QB | C1QBP | C1QC | C1QL1 | C1QL2 | C1QL3 | C1QL4 | C1QTNF1 | C1QTNF1-AS1 | C1QTNF12 | C1QTNF2 | C1QTNF3 | C1QTNF3-AMACR | C1QTNF4 | C1QTNF5 | C1QTNF6 | C1QTNF7 | C1QTNF7-AS1 | C1QTNF8 | C1QTNF9 | C1QTNF9B | C1R | C1RL | C1RL-AS1 | C1S | C2 | C2-AS1 | C20orf141 | C20orf144 | C20orf173 | C20orf181 | C20orf202 | C20orf203 | C20orf204 | C20orf27 | C20orf85 | C20orf96 | C21orf58 | C21orf62 | C21orf62-AS1 | C21orf91 | C21orf91-OT1 | C22orf15 | C22orf23 | C22orf31 | C22orf39 | C22orf42 | C22orf46P | C2CD2 | C2CD2L | C2CD3 | C2CD4A | C2CD4B | C2CD4C | C2CD4D | C2CD4D-AS1 | C2CD5 | C2CD6 | C2orf15 | C2orf16 | C2orf27A | C2orf42 | C2orf48 | C2orf49 | C2orf50 | C2orf66 | C2orf68 | C2orf69 | C2orf72 | C2orf73 | C2orf74 | C2orf74-DT | C2orf76 | C2orf78 | C2orf80 | C2orf81 | C2orf83 | C2orf88 | C2orf92 | C3 | C3AR1 | C3orf14 | C3orf18 | C3orf20