C2orf69: A promising drug target and biomarker for Mitochondrial Protein 69

Target Name: C2orf69

NCBI ID: G205327

C2orf69

C2orf69: A promising drug target and biomarker for Mitochondrial Protein 69

Mitochondria are essential organelles that play a crucial role in the cell's energy metabolism. They are the primary powerhouses for the cell, producing the majority of ATP, the energy currency of the cell. Damage to mitochondria can lead to a range of disorders, including Alzheimer's disease, Parkinson's disease, and motor neuron disease. Therefore, it is crucial to identify and target the proteins that are involved in the pathophysiology of these disorders. C2orf69 is a protein that has been identified as a potential drug target and biomarker for Mitochondrial Protein 69 (MP69). This article will discuss the biology of C2orf69, its potential implications as a drug target, and its potential as a biomarker for MP69-related disorders.

Biochemistry and Proteomics

C2orf69 is a 69 kDa protein that is encoded by the gene ORF69. It is located at the cytoplasmic side of the mitochondria and is involved in various cellular processes, including the production of ATP, protein folding, and translation of mRNAs. C2orf69 is composed of 105 amino acid residues and has a calculated pI of 11.99. It is expressed in a variety of tissues, including muscle, heart, brain, and liver.

Expression and Therapeutic Potential

C2orf69 has been shown to play a crucial role in the pathophysiology of various disorders, including Alzheimer's disease, Parkinson's disease, and motor neuron disease. Its involvement in these disorders has led to its potential as a drug target. C2orf69 has been shown to be involved in the production of reactive oxygen species (ROS), which can damage cellular components and contribute to the pathophysiology of these disorders. Additionally, C2orf69 has been shown to play a role in the regulation of mitochondrial dynamics, which is important for the proper functioning of the mitochondria.

C2orf69 has also been shown to be a potential biomarker for several disorders, including Alzheimer's disease and Parkinson's disease. Its expression has been shown to be affected in these disorders, which may indicate its potential as a biomarker. C2orf69 has been shown to be expressed in the brains of individuals with Alzheimer's disease and has been shown to be involved in the production of ROS, which can contribute to the pathophysiology of this disorder. Similarly, C2orf69 has been shown to be expressed in the brains of individuals with Parkinson's disease, and its expression may be involved in the pathophysiology of this disorder.

Drug Targeting

C2orf69 has been shown to be a potential drug target by several studies. Its involvement in the production of ROS and its involvement in the regulation of mitochondrial dynamics make it an attractive target for inhibitors that can reduce ROS production and increase mitochondrial function. Several studies have shown that inhibitors that can inhibit C2orf69 can protect against the damage caused by ROS in cell culture models of Alzheimer's disease and Parkinson's disease.

Biomarker Potential

C2orf69 has also been shown to be a potential biomarker for several disorders, including Alzheimer's disease and Parkinson's disease. Its expression has been shown to be affected in these disorders, which may indicate its potential as a biomarker. C2orf69 has been shown to be expressed in the brains of individuals with Alzheimer's disease and has been shown to be involved in the production of ROS, which can contribute to the pathophysiology of this disorder. Similarly, C2orf69 has been shown to be expressed in the brains of individuals with Parkinson's disease, and its expression may be involved in the pathophysiology of this disorder

Protein Name: Chromosome 2 Open Reading Frame 69

Functions: May play a role in the respiratory chain

The "C2orf69 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C2orf69 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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