MXD3: A Protein Target for Cancer and Neurodegenerative Diseases

Target Name: MXD3

NCBI ID: G83463

MXD3

MXD3: A Protein Target for Cancer and Neurodegenerative Diseases

MXD3, also known as Max-associated protein 3, is a protein that is expressed in various tissues throughout the body. It is a member of the superfamily of transmembrane protein and is involved in various cellular processes such as intracellular signaling, inflammation, and stress responses. MXD3 has also been implicated in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, MXD3 has emerged as a promising drug target and biomarker for a variety of diseases.

MXD3 is composed of 115 amino acid residues and has a calculated molecular weight of 13.9 kDa. It is expressed in a variety of tissues, including brain, heart, liver, and muscle. MXD3 is primarily localized to the endoplasmic reticulum (ER) and is predominantly expressed in the cytoplasm of cells. It is a glycoprotein and has a high degree of acidity, which allows it to interact with various signaling molecules.

MXD3 is involved in several cellular processes that are crucial for maintaining cellular homeostasis. One of its key functions is to regulate protein synthesis and degradation. It is a transcription factor that binds to DNA and enhances the activity of several RNA polymerases, including RNA polymerase II (RNA-II). RNA-II is responsible for transcribing the DNA code into proteins, and MXD3 has been shown to play a role in regulating the levels of various proteins in the cell.

Another function of MXD3 is to regulate cell signaling pathways. It is involved in several signaling pathways that are important for cellular growth, differentiation, and survival. For example, MXD3 is involved in the regulation of the Wnt signaling pathway, which is important for the development and maintenance of tissues. It is also involved in the regulation of the TGF-β signaling pathway, which is important for cell growth, differentiation, and stress responses.

MXD3 is also involved in the regulation of inflammation and stress responses. It is a signaling molecule that is involved in the regulation of inflammation and stress responses. For example, MXD3 is involved in the regulation of the production of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾. It is also involved in the regulation of the production of anti-inflammatory cytokines, such as IL-10.

In addition to its role in cellular signaling pathways, MXD3 is also a potential drug target. Its high degree of acidity and its ability to interact with various signaling molecules make it an attractive target for small molecules. Several studies have shown that MXD3 can be inhibited by small molecules, including inhibitors of protein synthesis, inhibitors of protein degradation, and inhibitors of signaling pathways. These inhibitors have been shown to have a variety of therapeutic effects, including the inhibition of cancer growth and the regulation of neurodegenerative diseases.

In conclusion, MXD3 is a protein that is involved in several cellular processes that are crucial for maintaining cellular homeostasis. Its role in regulating protein synthesis and degradation, cell signaling pathways, inflammation and stress responses makes it an attractive drug target. The inhibition of MXD3 by small molecules has been shown to have a variety of therapeutic effects, including the inhibition of cancer growth and the regulation of neurodegenerative diseases. Therefore, MXD3 is a promising drug target and biomarker for a variety of diseases.

Protein Name: MAX Dimerization Protein 3

Functions: Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity)

The "MXD3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MXD3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets