Target Name: MYO1H
NCBI ID: G283446
Review Report on MYO1H Target / Biomarker Content of Review Report on MYO1H Target / Biomarker
MYO1H
Other Name(s): myosin-Ih | unconventional myosin-Ih | Myosin IH | Myosin-1H | myosin IH | CCHS2 | myosin-1H | MYO1H_HUMAN | Unconventional myosin-Ih

MYO1H: Regulation of Myosin ATPase and Muscle Cell Function

Myosin-Ih (MYO1H) is a protein that plays a critical role in muscle cell function and growth. It is a key regulator of myosin ATPase (also known as actin-1), which is responsible for generating the energy required for muscle contractions. The protein encoded by the MYO1H gene activates and regulates ATPase activity in many muscle cells. MYO1H plays a key role in muscle contraction and relaxation in various physiological processes. However, MYO1H itself is also involved in regulating muscle cell growth and regeneration. Knockdown of MYO1H will lead to a decrease in muscle cell contraction and relaxation functions, thereby affecting exercise capacity.

MYO1H is a transmembrane protein with a high protein content in the cell membrane. It is composed of two subunits, each containing a hydrophobic helix. The hydrophobic helical structure of MYO1H enables it to bind to ATPase and regulate its activity.

The activation of MYO1H requires certain signal stimulation. When MYO1H binds to ATPase, the activity of ATPase is inhibited, resulting in contraction and relaxation of muscle cells. When MYO1H is activated, ATPase activity is inhibited, thereby promoting contraction and relaxation of muscle cells.

Knockdown of MYO1H will lead to a decrease in muscle cell contraction and relaxation functions, thereby affecting exercise capacity. Activation of MYO1H can enhance the contraction and relaxation functions of muscle cells, thereby improving exercise capacity.

The function of MYO1H in muscle cells is also regulated by other molecules. For example, MYO1H can be regulated by myoglobin (myoglobin). Myoglobin is a protein found in muscle cells that binds ATP with the help of MYO1H, thereby regulating ATPase activity.

MYO1H can also be regulated by other molecules. For example, MYO1H can be regulated by insulin (insulin). Insulin is a protein that plays an important role in the body. It can bind ATP with the help of MYO1H, thus regulating the activity of ATPase.

Research on MYO1H

The study of MYO1H is important for understanding the function of muscle cells. The activation and regulation of MYO1H helps people understand how muscle cells produce energy and adapt to the demands of exercise.

Currently, MYO1H is widely used in drug research and treatment. For example, MYO1H has been used as a treatment

Protein Name: Myosin IH

Functions: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity)

The "MYO1H Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MYO1H comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MYO3A | MYO3B | MYO3B-AS1 | MYO5A | MYO5B | MYO5C | MYO6 | MYO7A | MYO7B | MYO9A | MYO9B | MYOC | MYOCD | MYOD1 | MYOF | MYOG | MYOM1 | MYOM2 | MYOM3 | MYORG | Myosin | Myosin class II | Myosin light-chain phosphatase | MYOSLID | MYOSLID-AS1 | MYOT | MYOZ1 | MYOZ2 | MYOZ3 | MYPN | MYPOP | MYRF | MYRF-AS1 | MYRFL | MYRIP | MYSM1 | MYT1 | MYT1L | MYT1L-AS1 | MYZAP | MZB1 | MZF1 | MZF1-AS1 | MZT1 | MZT2A | MZT2B | N-acetylglucosamine-1-phosphotransferase | N-CoR deacetylase complex | N-Terminal Acetyltransferase A (NatA) Complex | N-Terminal Acetyltransferase C (NatC) Complex | N-Type Calcium Channel | N4BP1 | N4BP2 | N4BP2L1 | N4BP2L2 | N4BP2L2-IT2 | N4BP3 | N6AMT1 | NAA10 | NAA11 | NAA15 | NAA16 | NAA20 | NAA25 | NAA30 | NAA35 | NAA38 | NAA40 | NAA50 | NAA60 | NAA80 | NAAA | NAALAD2 | NAALADL1 | NAALADL2 | NAALADL2-AS3 | NAB1 | NAB2 | NABP1 | NABP2 | NACA | NACA2 | NACA3P | NACA4P | NACAD | NACC1 | NACC2 | NAD(P)H dehydrogenase, quinone | NAD-Dependent Protein Deacetylase | NADH dehydrogenase (Complex I) | NADK | NADK2 | NADPH Oxidase | NADPH Oxidase Complex | NADSYN1 | NAE1 | NAF1 | NAG18 | NAGA | NAGK