Target Name: MYO3B
NCBI ID: G140469
Review Report on MYO3B Target / Biomarker Content of Review Report on MYO3B Target / Biomarker
MYO3B
Other Name(s): Myosin IIIB, transcript variant 1 | Myosin-IIIb | MYO3B_HUMAN | OTTHUMP00000237453 | Myosin IIIB, transcript variant 2 | MYO3B variant 1 | OTTHUMP00000204844 | OTTHUMP00000204843 | MYO3B variant 2 | Myosin-IIIb (isoform 1) | myosin IIIB | Myosin-IIIb (isoform 2) | OTTHUMP00000204841 | OTTHUMP00000204848

MYO3B: A Potential Drug Target for Muscle Contraction and Relaxation

Myosin IIIB (MYO3B) is a protein that plays a crucial role in muscle contraction and relaxation. It is a key component of the myosin filament, which is the protein complex that powers muscle movement. MYO3B has been identified as a potential drug target and has been shown to be involved in a variety of physiological processes in the body. In this article, we will explore the biology and potential drug targets of MYO3B.

Biology

MYO3B is a 25 kDa protein that is expressed in a variety of tissues, including muscle, heart, and brain. It is a key component of the myosin filament, which is the protein complex that powers muscle movement. MYO3B helps to regulate the length and stability of myosin filaments, which are essential for muscle contraction and relaxation.

MYO3B has been shown to play a role in a variety of physiological processes in the body. It has been shown to be involved in muscle development and maintenance, as well as in the regulation of cellular signaling pathways. It has also been shown to be involved in the development and maintenance of heart muscle, which is critical for maintaining blood pressure and circulating blood throughout the body.

Drug Targets

MYO3B is a potential drug target because of its involvement in a variety of physiological processes. One of the main targets for MYO3B is the regulation of myosin filament dynamics. This is an important target because myosin filaments are involved in muscle contraction and relaxation. By regulating myosin filament dynamics, MYO3B can be targeted to improve muscle function and reduce the risk of muscle-related injuries.

Another potential target for MYO3B is the regulation of cellular signaling pathways. MYO3B has been shown to be involved in a variety of signaling pathways, including the regulation of cell division, cell growth, and protein synthesis. By targeting these pathways, MYO3B may be able to contribute to the regulation of cellular behavior and the prevention of a variety of diseases.

MYO3B has also been shown to be involved in the regulation of inflammation. Inflammation is a critical response of the immune system to injury or infection, and it can contribute to the development of a variety of diseases. By targeting MYO3B, drugs may be able to reduce inflammation and improve overall health.

Conclusion

MYO3B is a protein that plays a crucial role in muscle contraction and relaxation. It is a key component of the myosin filament and has been shown to be involved in a variety of physiological processes in the body. As a result, MYO3B is a potential drug target and has the potential to contribute to the treatment of a variety of diseases. Further research is needed to fully understand the biology and potential drug targets of MYO3B.

Protein Name: Myosin IIIB

Functions: Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments

The "MYO3B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MYO3B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MYO3B-AS1 | MYO5A | MYO5B | MYO5C | MYO6 | MYO7A | MYO7B | MYO9A | MYO9B | MYOC | MYOCD | MYOD1 | MYOF | MYOG | MYOM1 | MYOM2 | MYOM3 | MYORG | Myosin | Myosin class II | Myosin light-chain phosphatase | MYOSLID | MYOSLID-AS1 | MYOT | MYOZ1 | MYOZ2 | MYOZ3 | MYPN | MYPOP | MYRF | MYRF-AS1 | MYRFL | MYRIP | MYSM1 | MYT1 | MYT1L | MYT1L-AS1 | MYZAP | MZB1 | MZF1 | MZF1-AS1 | MZT1 | MZT2A | MZT2B | N-acetylglucosamine-1-phosphotransferase | N-CoR deacetylase complex | N-Terminal Acetyltransferase A (NatA) Complex | N-Terminal Acetyltransferase C (NatC) Complex | N-Type Calcium Channel | N4BP1 | N4BP2 | N4BP2L1 | N4BP2L2 | N4BP2L2-IT2 | N4BP3 | N6AMT1 | NAA10 | NAA11 | NAA15 | NAA16 | NAA20 | NAA25 | NAA30 | NAA35 | NAA38 | NAA40 | NAA50 | NAA60 | NAA80 | NAAA | NAALAD2 | NAALADL1 | NAALADL2 | NAALADL2-AS3 | NAB1 | NAB2 | NABP1 | NABP2 | NACA | NACA2 | NACA3P | NACA4P | NACAD | NACC1 | NACC2 | NAD(P)H dehydrogenase, quinone | NAD-Dependent Protein Deacetylase | NADH dehydrogenase (Complex I) | NADK | NADK2 | NADPH Oxidase | NADPH Oxidase Complex | NADSYN1 | NAE1 | NAF1 | NAG18 | NAGA | NAGK | NAGLU | NAGPA