Myosin X: A Key Protein in Muscle Contraction and Relaxation (G4651)

Target Name: MYO10

NCBI ID: G4651

MYO10

Myosin X: A Key Protein in Muscle Contraction and Relaxation

Myosin X (MYO10) is a protein that is expressed in muscle cells and is known for its role in muscle contraction and relaxation. It is a key protein in the myosin system, which is responsible for generating muscle force during physical activity.MYO10 has been identified as a potential drug target and biomarker for several muscle-related conditions, including muscle dystrophy, myopathies, and neuromuscular disorders.

Myosin X in Muscle contraction and relaxation

Myosin X is a key protein in the myosin system that plays a critical role in muscle contraction and relaxation. It is a member of the myosin light chain (MLC), which is the most abundant subunit of myosin in muscle cells. Myosin X is responsible for generating the power of muscle contractions by participating in the sliding of the myosin heads along the filaments.

During muscle contraction, myosin X helps to recruit new myosin heads to the actin filaments, where they begin to slide along and generate force. This process is known as myosin recruitment and is critical for generating muscle force. Once the myosin heads have recruited to the actin filaments, they begin to slide along the filaments, resulting in muscle contraction.

Myosin X is also involved in muscle relaxation, or muscle relaxation, which is the process by which muscle cells relax and prepare for the next muscle contraction. During muscle relaxation, myosin X helps to remove myosin heads from the actin filaments, allowing them to return to their original position. This process is critical for maintaining muscle tone and preventing muscle contractions that are too strong or too frequent.

Myosin X as a drug target

Myosin X has been identified as a potential drug target for several muscle-related conditions. One of the main reasons for this is the fact that myosin X is involved in many important physiological processes in muscle cells, including muscle contraction and relaxation. This means that drugs that can modulate myosin X activity could potentially have a wide range of therapeutic applications.

One of the key advantages of targeting myosin X is that it is a protein that is expressed in muscle cells, which makes it an attractive target for drugs that can modulate protein synthesis or degradation. This is because drugs that can modulate protein synthesis or degradation can potentially affect myosin X levels or activity in muscle cells.

Another advantage of targeting myosin X is that it is a protein that is involved in many important physiological processes in muscle cells. This means that drugs that can modulate myosin X activity could potentially have a wide range of therapeutic applications. For example, drugs that can modulate myosin X activity could potentially be used to treat muscle dystrophy, myopathies, and other muscle-related conditions.

Myosin X as a biomarker

In addition to its role in muscle contraction and relaxation, myosin X has also been identified as a potential biomarker for several muscle-related conditions. This is because myosin X is a protein that is expressed in muscle cells and can be used as a diagnostic marker for muscle-related conditions.

One of the main applications of myosin X as a biomarker is its ability to be used as a diagnostic marker for muscle-related conditions. For example, myosin X has been used as a biomarker for a variety of muscle-related conditions, including muscle dystrophy, myopathies, and neuromuscular disorders.

Another application of myosin X as a biomarker is its ability to be used as a target for drug development. Drugs that can modulate myosin X activity have the potential to be used to treat a wide range of muscle-related conditions. For example, drugs that can

Protein Name: Myosin X

Functions: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as a plus end-directed motor. Moves with higher velocity and takes larger steps on actin bundles than on single actin filaments (PubMed:27580874). The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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