THAP2 Regulates TNF-alpha-Induced Cellular Response (G83591)

Target Name: THAP2

NCBI ID: G83591

THAP2

Other Name(s): THAP2_HUMAN | THAP domain-containing protein 2 | THAP domain containing 2 | THAP domain containing, apoptosis associated protein 2

THAP2 Regulates TNF-alpha-Induced Cellular Response

THAP2 (Tumor necrosis factor-alpha-induced peroxidation of albumin) is a protein that is expressed in a variety of tissues, including the liver, lung, heart, and kidney. It is a key mediator of cellular responses to tumor necrosis factor-alpha (TNF-alpha), a cytokine that is secreted by the immune system in response to the presence of cancer cells.

THAP2 has been shown to play a role in a variety of physiological processes, including inflammation, fibrosis, and autophagy. It has also been shown to be involved in the regulation of cellular processes such as cell adhesion, migration, and survival. In addition, THAP2 has been shown to be a potential drug target in the treatment of a variety of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

One of the key functions of THAP2 is its role in the regulation of cellular responses to TNF-alpha. TNF-alpha is a cytokine that is involved in the immune response and has been implicated in a variety of diseases, including cancer, autoimmune diseases, and neurodegenerative diseases. In addition, TNF-alpha has been shown to play a role in the regulation of cellular processes such as cell adhesion, migration, and survival.

THAP2 is involved in the regulation of TNF-alpha-induced cellular responses by several mechanisms. First, it can inhibit the activity of TNF-alpha, reducing its ability to stimulate cellular responses. Second, it can activate the production of reactive oxygen species ( ROS), which can damage cellular components and contribute to cellular stress. Third, it can regulate the expression of genes involved in the TNF-alpha signaling pathway, including the transcription factor

Protein Name: THAP Domain Containing 2

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