TIAM1-AS1: A Potential Drug Target and Biomarker (G150051)

Target Name: TIAM1-AS1

NCBI ID: G150051

TIAM1-AS1

Other Name(s): Uncharacterized protein LOC150051 | LOC150051 | TIAM1 antisense RNA 1 | Uncharacterized LOC150051

TIAM1-AS1: A Potential Drug Target and Biomarker

Introduction

Protein biomarkers are gaining significant attention in the pharmaceutical industry due to their potential as drug targets. These biomarkers can be derived from various cellular components, including cytosomes, endoplasmic reticulum, and other secretory organelles. One such protein is TIAM1-AS1, which is a unique protein identified by the LOC150051 gene. In this article, we will explore the potential implications of TIAM1-AS1 as a drug target and biomarker.

Structure and Localization

TIAM1-AS1 is a 21.1 kDa protein that is expressed in various cell types, including muscle, liver, and brain. It is characterized by a unique N-terminus that contains a conserved domain known as the N-end rule (NER) domain. The NER domain is a common feature in proteins that plays a critical role in protein-protein interactions and is involved in the regulation of protein stability and localization.

The second relative molecular mass region (R2) of TIAM1-AS1 contains a unique domain known as the B-sheet domain. This domain is known for its ability to form a stable interaction with various ligands, including small molecules, ions, and other proteins . The B-sheet domain also displays a higher degree of flexibility, which allows it to accommodate different types of interactions.

The C-terminus of TIAM1-AS1 contains a conserved region known as the C-end rule (CER) domain. This domain is involved in the regulation of protein-protein interactions and also functions as a binding site for various ligands.

Function and Localization

TIAM1-AS1 is involved in various cellular processes, including cell signaling, protein folding, and cytoskeletal organization. It is a key protein that contributes to the regulation of the actinin filament, which is a protein that plays a critical role in cell signaling and cytoskeletal organization.

Recent studies have suggested that TIAM1-AS1 may be a drug target due to its unique structure and function. The NER domain and B-sheet domain have been shown to interact with various ligands, including small molecules and other proteins. This suggests that TIAM1- AS1 may be a target for small molecules or other drugs that can modulate its activity.

In addition to its potential as a drug target, TIAM1-AS1 has also been shown to be a potential biomarker. The protein is expressed in various cell types and can be used as a protein biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Molecular Model and Theoretical Predictions

To better understand the structure and function of TIAM1-AS1, several molecular models have been created. One of the most accurate models is the protein structure prediction, which is based on the known amino acid sequence of the protein. Using this method, several researchers have predicted the three-dimensional structure of TIAM1-AS1.

The predicted structure of TIAM1-AS1 is characterized by a unique arrangement of amino acids. The protein has a distinct N-end rule domain that is located at the N-terminus. The NER domain is involved in the regulation of protein stability and localization, and its presence suggests that TIAM1-AS1 is involved in various cellular processes that involve protein stability and localization.

The B-sheet domain is located in the middle of the protein and is characterized by a higher degree of flexibility. This suggests that TIAM1-AS1 is involved in various protein-protein interactions that require a high degree of flexibility.

The C-end rule domain is located at the C-terminus of the protein and is involved in protein-protein interactions. This suggests that TIAM1-AS1 is involved in various protein-protein interactions that are critical for

Protein Name: TIAM1 Antisense RNA 1

The "TIAM1-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TIAM1-AS1 comprehensively, including but not limited to:
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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