Target Name: THTPA
NCBI ID: G79178
Review Report on THTPA Target / Biomarker Content of Review Report on THTPA Target / Biomarker
THTPA
Other Name(s): THTPA_HUMAN | ThTPase | THTPASE | THTPA variant 1 | Thiamine-triphosphatase (isoform 1) | thiamine triphosphatase | Thiamine-triphosphatase | MGC2652 | THTP | Thiamine triphosphatase, transcript variant 1

THTPA: A Protein Involved in Cellular Processes and Disease Development

THTPA (THTPA_HUMAN), also known as 2-[(2-Mercaptoethoxy)dimethyl]-1-[(2-methylpropyl)amino]-1-propanethiol, is a protein that is expressed in various tissues of the human body. It is involved in the regulation of cellular processes such as cell adhesion, migration, and invasion, and has been implicated in the development and progression of various diseases, including cancer.

THTPA is a member of the tight junction protein family, which is responsible for maintaining the integrity of the intercellular barrier and preventing unauthorized access to the body's tissues. It plays a crucial role in this function by helping cells interact with the surrounding matrix, thereby Regulates the interaction of cells with their surrounding environment.

THTPA is involved in many different cellular processes in the body, including the regulation of cell adhesion and migration. It has been shown to play a role in the development and maintenance of tight junctions, which are specialized barriers that separate cells from their surrounding tissues. Tight junctions help to ensure that substances cannot enter or leave cells, and are essential for maintaining the integrity of the intercellular barrier.

THTPA is also involved in the regulation of cell division and the association with the development of cancer. It has been shown to promote the growth and division of cancer cells, and is often overexpressed in various types of cancer. Additionally, it has been linked to the development of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases.

THTPA has also been shown to play a role in the regulation of inflammation and pain. It has been shown to contribute to the recruitment of immune cells to the site of inflammation and to participate in the regulation of pain signaling.

Due to its involvement in so many different cellular processes, THTPA has potential as a drug target or biomarker. For example, it has been shown to be a useful target for small molecules such as inhibitors, and has been shown to be involved in various signaling pathways that are involved in cancer and neurodegenerative diseases.

In conclusion, THTPA is a protein that plays a crucial role in the regulation of various cellular processes in the body. Its involvement in cell adhesion, migration, and the development of cancer, as well as its potential as a drug target or biomarker, make it an attractive target for research into the development of new treatments for a variety of diseases.

Protein Name: Thiamine Triphosphatase

Functions: Hydrolase highly specific for thiamine triphosphate (ThTP)

The "THTPA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about THTPA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

THUMPD1 | THUMPD2 | THUMPD3 | THUMPD3-AS1 | THY1 | Thymidine Kinase | THYN1 | Thyroid hormone receptor | Thyrostimulin | Thyrotropin | TIA1 | TIAF1 | TIAL1 | TIAM1 | TIAM1-AS1 | TIAM2 | TICAM1 | TICAM2 | TICAM2-AS1 | TICRR | Tie Receptor | TIE1 | TIFA | TIFAB | TIGAR | TIGD1 | TIGD2 | TIGD3 | TIGD4 | TIGD5 | TIGD6 | TIGD7 | TIGIT | TIM22 complex | TIM23 Complex | TIMD4 | TIMELESS | TIMM10 | TIMM10B | TIMM13 | TIMM17A | TIMM17B | TIMM21 | TIMM22 | TIMM23 | TIMM29 | TIMM44 | TIMM50 | TIMM8-TIMM13 complex | TIMM8A | TIMM8AP1 | TIMM8B | TIMM9 | TIMMDC1 | TIMP1 | TIMP2 | TIMP3 | TIMP4 | TINAG | TINAGL1 | TINCR | TINF2 | TIPARP | TIPARP-AS1 | TIPIN | TIPRL | TIRAP | TIRAP-AS1 | TJAP1 | TJP1 | TJP2 | TJP3 | TK1 | TK2 | TKFC | TKT | TKTL1 | TKTL2 | TLCD1 | TLCD2 | TLCD3A | TLCD3B | TLCD4 | TLCD4-RWDD3 | TLCD5 | TLDC2 | TLE1 | TLE1-DT | TLE2 | TLE3 | TLE4 | TLE5 | TLE6 | TLK1 | TLK2 | TLL1 | TLL2 | TLN1 | TLN2 | TLNRD1