Target Name: TTR
NCBI ID: G7276
Review Report on TTR Target / Biomarker Content of Review Report on TTR Target / Biomarker
TTR
Other Name(s): ATTR | TTHY_HUMAN | TTN | thyroxine-binding prealbumin | CTS1 | PALB | HsT2651 | epididymis luminal protein 111 | Prealbumin | transthyretin | Transthyretin | CTS | prealbumin, amyloidosis type I | TBPA | HEL111

TTR: A Protein with Potential for Revolutionizing Disease Treatment and Diagnosis

TTR (short for Tissue Response) is a protein that is expressed in various tissues throughout the body, including the lungs, heart, kidneys, and intestines. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, fibrosis, and autoimmune disorders.

One of the unique aspects of TTR is its ability to cross the blood-brain barrier, which is a barrier that separates the brain from the rest of the body and is designed to protect it from harmful substances. This ability makes TTR a promising drug target for a number of diseases, including Alzheimer's and Parkinson's.

Research has shown that TTR is involved in a number of important cellular processes in the brain, including the regulation of neurotransmitter signaling, cell survival, and inflammation. It has also been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's.

One of the key challenges in studying TTR is its complex structure and the difficulty of modifying it to produce specific effects. Researchers have developed a number of techniques to study TTR, including knockout mice, RNA interference, and mass spectrometry. These techniques have allowed them to identify the key factors that regulate TTR function and to understand its role in various diseases.

In addition to its potential as a drug target, TTR is also a potential biomarker for a number of diseases. Its expression has been detected in a variety of diseases, including cancer, fibrosis, and autoimmune disorders. By studying the levels and patterns of TTR in these diseases, researchers may be able to develop new diagnostic tests and treatments.

Overall, TTR is a protein that has the potential to revolutionize our understanding of a variety of diseases. Its complex structure and ability to cross the blood-brain barrier make it an attractive target for drug development, and its role in the regulation of cellular processes in the brain makes it an important player in the study of neurodegenerative diseases. Further research is needed to fully understand its function and potential as a drug and biomarker.

Protein Name: Transthyretin

Functions: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain

The "TTR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TTR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TTT Complex | TTTY1 | TTTY10 | TTTY11 | TTTY13 | TTTY14 | TTTY15 | TTTY16 | TTTY17A | TTTY17B | TTTY19 | TTTY2 | TTTY20 | TTTY21 | TTTY22 | TTTY4B | TTTY4C | TTTY5 | TTTY6 | TTTY7 | TTTY8 | TTTY9A | TTYH1 | TTYH2 | TTYH3 | TUB | TUBA1A | TUBA1B | TUBA1B-AS1 | TUBA1C | TUBA3C | TUBA3D | TUBA3E | TUBA3FP | TUBA4A | TUBA4B | TUBA8 | TUBAL3 | TUBAP2 | TUBAP7 | TUBB | TUBB1 | TUBB2A | TUBB2B | TUBB2BP1 | TUBB3 | TUBB4A | TUBB4B | TUBB6 | TUBB7P | TUBB8 | TUBB8P2 | TUBB8P7 | TUBBP1 | TUBBP2 | TUBBP3 | TUBBP5 | TUBBP6 | TUBD1 | TUBE1 | TUBG1 | TUBG1P | TUBG2 | TUBGCP2 | TUBGCP3 | TUBGCP4 | TUBGCP5 | TUBGCP6 | Tubulin | TUFM | TUFMP1 | TUFT1 | TUG1 | TULP1 | TULP2 | TULP3 | TULP4 | Tumor Necrosis Factor Receptor Superfamily Member 10 (TRAIL-R) | Tumor-Associated Glycoprotein 72 (TAG-72) | TUNAR | TUSC1 | TUSC2 | TUSC2P1 | TUSC3 | TUSC7 | TUSC8 | TUT1 | TUT4 | TUT7 | TVP23A | TVP23B | TVP23C | TVP23C-CDRT4 | TVP23CP2 | TWF1 | TWF2 | TWIST | TWIST1 | TWIST2 | TWNK