FPGT: A Key Enzyme in Fucose Metabolism and Cancer Development

Target Name: FPGT

NCBI ID: G8790

FPGT

FPGT: A Key Enzyme in Fucose Metabolism and Cancer Development

Fucose-1-phosphate guanyltransferase isoform 1 (FPGT) is a protein that plays a crucial role in the metabolism of fucose, a type of sugar found in many foods, including fruits, vegetables, and legumes. FPGT is an enzyme that catalyzes the transfer of a phosphate group from a fucose molecule to a guanyl group, which is a key structural unit in the amino acid glycine.

The ability of FPGT to transfer the phosphate group to guanyl groups is a critical function for the proper functioning of many cellular processes in the body. FPGT is involved in the regulation of a wide range of cellular processes, including cell signaling, DNA replication, and metabolism.

One of the unique features of FPGT is its role in the metabolism of fucose in the brain. Fucose is a major source of energy for the brain, and the ability of FPGT to properly transfer the phosphate group to guanyl groups is crucial for the brain to function properly.

FPGT has also been shown to play a key role in the development and progression of a number of diseases, including cancer. In particular, FPGT has been shown to be involved in the regulation of the angiogenesis (the formation of new blood vessels) that occurs in the development of cancer.

Due to its involvement in so many cellular processes, FPGT has been identified as a potential drug target or biomarker for a wide range of diseases. Researchers are currently working to develop new treatments for a variety of conditions that are dependent on the proper function of FPGT.

In addition to its role in the brain and its involvement in cancer development, FPGT is also of interest to researchers as a potential therapeutic target for a number of other diseases. For example, FPGT has been shown to be involved in the regulation of inflammation, and researchers are currently working to develop new treatments for a variety of inflammatory disorders.

Overall, FPGT is a protein that plays a critical role in many cellular processes in the body. Its ability to transfer the phosphate group to guanyl groups is a crucial function for the proper functioning of many cellular processes, including the metabolism of fucose and the development and progression of cancer. As a result, FPGT is a protein that is of great interest to researchers as a potential drug target or biomarker for a wide range of diseases.

Protein Name: Fucose-1-phosphate Guanylyltransferase

Functions: Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate (PubMed:9804772). Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids (PubMed:9804772)

The "FPGT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FPGT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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