Target Name: FRK
NCBI ID: G2444
Review Report on FRK Target / Biomarker Content of Review Report on FRK Target / Biomarker
FRK
Other Name(s): fyn related Src family tyrosine kinase | FYN-related kinase | protein-tyrosine kinase 5 | Fyn related Src family tyrosine kinase | RAK | PTK5 protein tyrosine kinase 5 | nuclear tyrosine protein kinase RAK | GTK | FRK variant X2 | FRK_HUMAN | Protein-tyrosine kinase 5 | fyn-related kinase | Frk Kinase | PTK5 | Nuclear tyrosine protein kinase RAK | Tyrosine-protein kinase FRK (isoform X1) | Tyrosine-protein kinase FRK | Frk kinase | Tyrosine-protein kinase FRK, transcript variant X2

FRK: A Protein Involved in Cell Signaling and Disease Development

FRK (Fyn-related Src family tyrosine kinase) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the Src family of proteins, which are known for their role in cell signaling.

FRK has been shown to play a role in a variety of physiological processes in the body, including the regulation of cell growth, differentiation, and survival. It is also involved in the development and progression of a number of diseases, including cancer.

Due to its involvement in so many important processes in the body, FRK has been identified as a potential drug target. Researchers are currently working to develop small molecules that can inhibit the activity of FRK, with the goal of using these drugs to treat a variety of diseases.

One of the challenges in studying FRK is its complex structure. FRK is a protein that contains multiple domains, including an extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain is involved in interactions with other proteins, while the transmembrane domain is responsible for the protein's ability to cross the membrane and interact with its intracellular domain.

While much research has been done on the structure and function of FRK, much of it is still unknown. However, studies have shown that FRK is involved in a number of important signaling pathways in the body.

One of the key functions of FRK is its role in cell signaling. FRK is involved in the regulation of cell growth and differentiation, as well as the regulation of cell survival. It is also involved in the development and progression of a number of diseases, including cancer.

FRK is involved in the regulation of cell growth and differentiation by promoting the production of new cells and by inhibiting the destruction of cells. This is accomplished through its ability to interact with and regulate the activity of other proteins, including the factors that promote cell growth and differentiation.

FRK is also involved in the regulation of cell survival by preventing the destruction of cells that are damaged or stressed. This is accomplished through its ability to interact with and regulate the activity of other proteins, including the factors that promote cell death.

In addition to its role in cell signaling, FRK is also involved in the development and progression of a number of diseases. For example, FRK has been shown to be involved in the development of cancer, and it is also involved in the regulation of the growth and development of blood vessels.

Due to its involvement in so many important processes in the body, FRK has been identified as a potential drug target. Researchers are currently working to develop small molecules that can inhibit the activity of FRK, with the goal of using these drugs to treat a variety of diseases.

One of the challenges in studying FRK is its complex structure. FRK is a protein that contains multiple domains, including an extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain is involved in interactions with other proteins, while the transmembrane domain is responsible for the protein's ability to

Protein Name: Fyn Related Src Family Tyrosine Kinase

Functions: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor

The "FRK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FRK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FRMD1 | FRMD3 | FRMD3-AS1 | FRMD4A | FRMD4B | FRMD5 | FRMD6 | FRMD6-AS1 | FRMD6-AS2 | FRMD7 | FRMD8 | FRMD8P1 | FRMPD1 | FRMPD2 | FRMPD2B | FRMPD3 | FRMPD4 | FRRS1 | FRRS1L | FRS2 | FRS3 | Fructose-Bisphosphate Aldolase | FRY | FRY-AS1 | FRYL | FRZB | FSBP | FSCB | FSCN1 | FSCN2 | FSCN3 | FSD1 | FSD1L | FSD2 | FSHB | FSHR | FSIP1 | FSIP2 | FSIP2-AS2 | FST | FSTL1 | FSTL3 | FSTL4 | FSTL5 | FTCD | FTCDNL1 | FTH1 | FTH1P1 | FTH1P10 | FTH1P11 | FTH1P12 | FTH1P2 | FTH1P20 | FTH1P22 | FTH1P24 | FTH1P3 | FTH1P4 | FTH1P5 | FTH1P7 | FTH1P8 | FTHL17 | FTL | FTLP16 | FTLP2 | FTLP3 | FTLP7 | FTMT | FTO | FTO-IT1 | FTOP1 | FTSJ1 | FTSJ3 | FTX | FUBP1 | FUBP3 | FUCA1 | FUCA2 | Fucosyl GM1 | Fucosyltransferase | FUNDC1 | FUNDC2 | FUNDC2P2 | FUNDC2P3 | FUOM | FURIN | FUS | FUT1 | FUT10 | FUT11 | FUT2 | FUT3 | FUT4 | FUT5 | FUT6 | FUT7 | FUT8 | FUT8-AS1 | FUT9 | FUZ | FXN