Target Name: RSPH1
NCBI ID: G89765
Review Report on RSPH1 Target / Biomarker Content of Review Report on RSPH1 Target / Biomarker
RSPH1
Other Name(s): TSA2 | Testes specific gene A2 homolog | Radial spoke head 1 homolog (isoform 1) | Radial spoke head 1 homolog | CILD24 | Radial spoke head component 1, transcript variant 1 | Testis specific A2 homolog | CT79 | Male meiotic metaphase chromosome-associated acidic protein | RSP44 | Meichroacidin | testes specific gene A2 homolog | RSPH1 variant 1 | cancer/testis antigen 79 | meichroacidin | RSPH10A | RSPH1_HUMAN | TSGA2 | Testes specific A2 homolog | Testis-specific gene A2 protein | radial spoke head component 1 | H-meichroacidin | male meiotic metaphase chromosome-associated acidic protein | testis specific A2 homolog | Cancer/testis antigen 79

Targeting RSPH1: A Potential Drug Treatment for Cancer and Other Diseases

The protein RSPH1 (resistance protein) is a key regulator of the Shh gene, which is involved in the development and maintenance of tissues during development and tissue repair. RSPH1 has also been implicated in the regulation of cell proliferation and survival.

Recent studies have identified RSPH1 as a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is due to the fact that RSPH1 has been shown to play a role in the regulation of cellular processes that are often disrupted in these diseases, such as cell proliferation, angiogenesis, and inflammation.

Drugs that target RSPH1 have been shown to be effective in preclinical studies, with some drugs showing promise in clinical trials. However, the use of these drugs in humans remains a challenge, and further research is needed to determine their safety and effectiveness.

The Protein RSPH1

RSPH1 is a protein that is expressed in a wide range of tissues and cells throughout the body. It is a member of the TSA2 family, which includes proteins that are involved in the regulation of cell survival and proliferation. RSPH1 is characterized by a N- terminus that contains a putative G protein-coupled receptor (GPCR) domain, as well as a C-terminus that contains a conserved Co-repeat domain.

The N-terminus of RSPH1 contains a GPCR domain that is involved in the regulation of cellular processes, including the regulation of cell adhesion, migration, and survival. The GPCR domain is a common feature of proteins that are involved in signaling pathways, and it is thought to play a role in the regulation of cellular processes that are critical for tissue development and maintenance.

The C-terminus of RSPH1 contains a conserved Co-repeat domain, which is a common feature of proteins that are involved in cell signaling. The Co-repeat domain is thought to play a role in the regulation of cellular processes, including the regulation of cell adhesion, migration, and survival.

RSPH1's Role in Cellular Processes

RSPH1 is involved in the regulation of a wide range of cellular processes, including cell adhesion, migration, and survival. It has been shown that RSPH1 plays a role in the regulation of cell-cell adhesion, and that it is involved in the development and maintenance of tight junctions, which are a type of cell-cell adhesion structure.

RSPH1 has also been shown to play a role in the regulation of cell migration. During development, RSPH1 is involved in the regulation of the movement of cells along the gradient of a chemotactic factor, and it is thought to play a role in the development of tissues that are ordered in their arrangement.

In addition to its role in cell adhesion and migration, RSPH1 is also involved in the regulation of cell survival. It has been shown that RSPH1 plays a role in the regulation of cell survival by controlling the levels of the cytoskeleton, which is a structure that helps to maintain cell shape and stability.

Drugs that Target RSPH1

Several drugs that have been shown to target RSPH1 have shown promise in preclinical studies. These drugs include:

1. Trastuzumab emtansine (T-DM1): This is a drug that is used to treat breast cancer. It is thought to work by targeting

Protein Name: Radial Spoke Head Component 1

Functions: Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia

The "RSPH1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RSPH1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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RSPH10B | RSPH14 | RSPH3 | RSPH4A | RSPH6A | RSPH9 | RSPO1 | RSPO2 | RSPO3 | RSPO4 | RSPRY1 | RSRC1 | RSRC2 | RSRP1 | RSU1 | RSU1P2 | RTBDN | RTCA | RTCB | RTEL1 | RTEL1-TNFRSF6B | RTF1 | RTF2 | RTKN | RTKN2 | RTL1 | RTL10 | RTL3 | RTL4 | RTL5 | RTL6 | RTL8A | RTL8B | RTL8C | RTL9 | RTN1 | RTN2 | RTN3 | RTN4 | RTN4IP1 | RTN4R | RTN4RL1 | RTN4RL2 | RTP1 | RTP2 | RTP3 | RTP4 | RTP5 | RTRAF | RTTN | RUBCN | RUBCNL | RUFY1 | RUFY2 | RUFY3 | RUFY4 | RUNDC1 | RUNDC3A | RUNDC3A-AS1 | RUNDC3B | RUNX1 | RUNX1-IT1 | RUNX1T1 | RUNX2 | RUNX2-AS1 | RUNX3 | RUNX3-AS1 | RUSC1 | RUSC1-AS1 | RUSC2 | RUSF1 | RUVBL1 | RUVBL1-AS1 | RUVBL2 | RWDD1 | RWDD2A | RWDD2B | RWDD3 | RWDD3-DT | RWDD4 | RXFP1 | RXFP2 | RXFP3 | RXFP4 | RXRA | RXRB | RXRG | RXYLT1 | Ryanodine receptor | RYBP | RYK | RYR1 | RYR2 | RYR3 | RZZ complex | S100 Calcium Binding Protein | S100A1 | S100A10 | S100A11 | S100A11P1