Target Name: RUFY4
NCBI ID: G285180
Review Report on RUFY4 Target / Biomarker Content of Review Report on RUFY4 Target / Biomarker
RUFY4
Other Name(s): RUN and FYVE domain containing 4 | RUN and FYVE domain-containing protein 4 | RUN and FYVE domain containing 4, transcript variant 1 | ZFYVE31 | FLJ46536 | RUFY4_HUMAN | RUFY4 variant 1

RUFY4: A novel drug target and biomarker for the treatment of human diseases

Abstract:

RUFY4, a novel NAD+-dependent G protein-coupled receptor (GPCR), has been identified as a potential drug target and biomarker for the treatment of various human diseases. Its unique physiological function and diverse expression patterns across various tissues have made it an attractive target for the development of new therapeutics. In this article, we will review the current research on RUFY4, its potential drug targets, and its potential as a biomarker for disease diagnosis and management.

Introduction:

GPCRs are a family of transmembrane proteins that play a crucial role in cellular signaling. GPCRs are involved in various physiological processes, including sensory perception, neurotransmission, and hormone signaling. They are also known as natriuretics, which means they regulate sodium and water excretion in the body. RUFY4, a GPCR gene, has been identified as a potential drug target and biomarker for the treatment of human diseases.

Current research on RUFY4:

RUFY4 has been shown to play a crucial role in various physiological processes in the body. It is highly expressed in the brain and tests, and its expression is also observed in various tissues, including the lungs, heart, liver, and pancreas. RUFY4 has It has also been shown to regulate various physiological processes, including blood pressure, heart rate, and body temperature. It has also been shown to play a role in neurotransmission, including the regulation of neurotransmitter release and receptor function.

In addition to its physiological functions, RUFY4 has also been shown to be a potential drug target. The RUFY4 gene has been shown to be involved in various cellular signaling pathways, including the regulation of ion channels, protein kinase, and intracellular signaling pathways. Several studies have shown that inhibition of RUFY4 has been shown to have neuroprotective effects, including the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Potential drug targets:

RUFY4 has several potential drug targets, including the treatment of neurodegenerative diseases, pain, and inflammation. One of the most promising potential drug targets for RUFY4 is the treatment of Alzheimer's disease. Alzheimer's disease is a neurodegenerative disease that is characterized by the progressive accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain. The accumulation of these aggregates is thought to contribute to the destruction of nerve cells in the brain, leading to the symptoms of Alzheimer's disease.

RUFY4 has been shown to regulate the production of beta-amyloid plaques and neurofibrillary tangles in various cellular models of Alzheimer's disease. Studies have shown that inhibition of RUFY4 has been shown to have neuroprotective effects in animal models of Alzheimer's disease. Additionally, clinical trials have shown that RUFY4 inhibitors have been shown to have clinical benefits in patients with Alzheimer's disease.

Another potential drug target for RUFY4 is the treatment of pain. RUFY4 has been shown to be involved in the regulation of pain signaling in various cellular models. Studies have shown that inhibition of RUFY4 has been shown to have analgesic effects in animal models of pain. Additionally, clinical trials have shown that RUFY4 inhibitors have been shown to have clinical benefits in

Protein Name: RUN And FYVE Domain Containing 4

Functions: Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger

The "RUFY4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RUFY4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RUNDC1 | RUNDC3A | RUNDC3A-AS1 | RUNDC3B | RUNX1 | RUNX1-IT1 | RUNX1T1 | RUNX2 | RUNX2-AS1 | RUNX3 | RUNX3-AS1 | RUSC1 | RUSC1-AS1 | RUSC2 | RUSF1 | RUVBL1 | RUVBL1-AS1 | RUVBL2 | RWDD1 | RWDD2A | RWDD2B | RWDD3 | RWDD3-DT | RWDD4 | RXFP1 | RXFP2 | RXFP3 | RXFP4 | RXRA | RXRB | RXRG | RXYLT1 | Ryanodine receptor | RYBP | RYK | RYR1 | RYR2 | RYR3 | RZZ complex | S100 Calcium Binding Protein | S100A1 | S100A10 | S100A11 | S100A11P1 | S100A12 | S100A13 | S100A14 | S100A16 | S100A2 | S100A3 | S100A4 | S100A5 | S100A6 | S100A7 | S100A7A | S100A7L2 | S100A7P1 | S100A8 | S100A9 | S100B | S100G | S100P | S100PBP | S100Z | S1PR1 | S1PR1-DT | S1PR2 | S1PR3 | S1PR4 | S1PR5 | SAA1 | SAA2 | SAA2-SAA4 | SAA3P | SAA4 | SAAL1 | SAC3D1 | SACM1L | SACS | SACS-AS1 | SAE1 | SAFB | SAFB2 | SAG | SAGA complex | SAGE1 | SALL1 | SALL2 | SALL3 | SALL4 | SALL4P7 | SALRNA2 | SAMD1 | SAMD10 | SAMD11 | SAMD12 | SAMD12-AS1 | SAMD13 | SAMD14 | SAMD15