Target Name: RTEL1
NCBI ID: G51750
Review Report on RTEL1 Target / Biomarker Content of Review Report on RTEL1 Target / Biomarker
RTEL1
Other Name(s): PFBMFT3 | DKCB5 | Novel helicase-like | Regulator of telomere elongation helicase 1 | regulator of telomere elongation helicase 1 | RTEL1 variant 1 | NHL | KIAA1088 | DKCA4 | RTEL1 variant 2 | bK3184A7.3 | RTEL | Regulator of telomere length | Regulator of telomere elongation helicase 1, transcript variant 1 | RTEL1_HUMAN | Regulator of telomere elongation helicase 1 (isoform 1) | C20orf41 | Regulator of telomere elongation helicase 1, transcript variant 3 | Regulator of telomere elongation helicase 1 (isoform 2) | regulator of telomere length | Regulator of telomere elongation helicase 1, transcript variant 2 | RTEL1 variant 3 | Regulator of telomere elongation helicase 1 (isoform 3) | DKFZp434C013 | OTTHUMP00000221856

RTEL1: A Protein Involved in Tissue Development and Cancer Regulation

RTEL1 (PFBMFT3) is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. It is a member of the BMF-T (bone marrow-derived factors-T) family, which is known for Its role in the development and maintenance of tissues, including bone marrow, fat tissue, and heart muscle.

One of the unique features of RTEL1 is its ability to interact with several different transcription factors, including colony-stimulating factor 1 (CSF1), PDGF-BB, and NF-kappa-B. This makes it a promising target for the development of new drugs that can be used to treat a variety of diseases.

RTEL1 has also been shown to play a role in the regulation of cellular processes that are important for brain development and function. For example, studies have shown that RTEL1 can help to promote the migration of neural stem cells to the developing brain, and that it can also contribute to the formation of memory and learning in the brain.

In addition to its potential role in brain development and function, RTEL1 has also been shown to be involved in the regulation of cellular processes that are important for many other tissues and organs. For example, studies have shown that RTEL1 can help to control the growth and differentiation of various types of cancer cells, and that it can also play a role in the regulation of cell signaling pathways that are important for many different diseases, including heart disease and diabetes.

Given its unique ability to interact with multiple transcription factors and its role in the regulation of important cellular processes, RTEL1 is a promising target for the development of new drugs. Researchers are currently working to identify new small molecules that can modulate RTEL1's activity, and to determine the full extent of its role in the development and maintenance of tissues.

In conclusion, RTEL1 is a protein that is expressed in a variety of tissues and is involved in a number of important cellular processes. Its unique ability to interact with multiple transcription factors makes it a promising target for the development of new drugs that can be used to treat a variety of diseases. Further research is needed to fully understand the role of RTEL1 in the development and maintenance of tissues, and to identify new small molecules that can modulate its activity.

Protein Name: Regulator Of Telomere Elongation Helicase 1

Functions: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere

The "RTEL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RTEL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RTEL1-TNFRSF6B | RTF1 | RTF2 | RTKN | RTKN2 | RTL1 | RTL10 | RTL3 | RTL4 | RTL5 | RTL6 | RTL8A | RTL8B | RTL8C | RTL9 | RTN1 | RTN2 | RTN3 | RTN4 | RTN4IP1 | RTN4R | RTN4RL1 | RTN4RL2 | RTP1 | RTP2 | RTP3 | RTP4 | RTP5 | RTRAF | RTTN | RUBCN | RUBCNL | RUFY1 | RUFY2 | RUFY3 | RUFY4 | RUNDC1 | RUNDC3A | RUNDC3A-AS1 | RUNDC3B | RUNX1 | RUNX1-IT1 | RUNX1T1 | RUNX2 | RUNX2-AS1 | RUNX3 | RUNX3-AS1 | RUSC1 | RUSC1-AS1 | RUSC2 | RUSF1 | RUVBL1 | RUVBL1-AS1 | RUVBL2 | RWDD1 | RWDD2A | RWDD2B | RWDD3 | RWDD3-DT | RWDD4 | RXFP1 | RXFP2 | RXFP3 | RXFP4 | RXRA | RXRB | RXRG | RXYLT1 | Ryanodine receptor | RYBP | RYK | RYR1 | RYR2 | RYR3 | RZZ complex | S100 Calcium Binding Protein | S100A1 | S100A10 | S100A11 | S100A11P1 | S100A12 | S100A13 | S100A14 | S100A16 | S100A2 | S100A3 | S100A4 | S100A5 | S100A6 | S100A7 | S100A7A | S100A7L2 | S100A7P1 | S100A8 | S100A9 | S100B | S100G | S100P | S100PBP | S100Z