Target Name: SPAG9
NCBI ID: G9043
Review Report on SPAG9 Target / Biomarker Content of Review Report on SPAG9 Target / Biomarker
SPAG9
Other Name(s): c-Jun NH2-terminal kinase-associated leucine zipper protein | Protein highly expressed in testis | sperm associated antigen 9 | cancer/testis antigen 89 | SPAG9 variant 4 | PHET | CT89 | JNK-interacting protein 4 | C-Jun-amino-terminal kinase-interacting protein 4 | JIP4_HUMAN | proliferation-inducing gene 6 | Max-binding protein | JNK-associated leucine-zipper protein | C-Jun-amino-terminal kinase-interacting protein 4 (isoform 1) | Sperm associated antigen 9 | JNK interacting protein | PIG6 | Sperm associated antigen 9, transcript variant 2 | Proliferation-inducing gene 6 | Proliferation-inducing protein 6 | sperm associated antigen 9 variant 5 | Sperm-specific protein | Sunday driver 1 | sperm surface protein | lung cancer oncogene 4 | protein highly expressed in testis | JIP4 | HLC-6 | HSS | C-Jun-amino-terminal kinase-interacting protein 4 (isoform 3) | Sperm-associated antigen 9 | SPAG9 variant 3 | Mitogen-activated protein kinase 8-interacting protein 4 | Cancer/testis antigen 89 | Sperm associated antigen 9 variant 5 | SPAG9 variant 2 | Sperm surface protein | Sperm associated antigen 9, transcript variant 3 | C-Jun-amino-terminal kinase-interacting protein 4 (isoform 4) | JIP-4 | sunday driver 1 | JNK/SAPK-associated protein | human lung cancer oncogene 6 protein | SPAG9 variant 1 | Sperm associated antigen 9, transcript variant 1 | C-Jun-amino-terminal kinase-interacting protein 4 (isoform 2) | mitogen-activated protein kinase 8-interacting protein 4 | HLC4 | JLP | Human lung cancer oncogene 6 protein | Sperm associated antigen 9, transcript variant 4 | Lung cancer oncogene 4 | HLC-4 protein | HLC6

SPAG9: A Potential Drug Target and Biomarker for c-Jun NH2-Terminal Kinase-Associated Leucine Zipper Protein

SPAG9, short for SPG9, is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. SPAG9 is associated with the c-Jun NH2-terminal kinase (CJK), which is a protein that plays a critical role in cell signaling and is involved in the development and progression of many diseases.

The c-Jun NH2-terminal kinase is a protein that is expressed in many different tissues and is involved in the regulation of a wide range of cellular processes, including cell growth, apoptosis, and angiogenesis. The CJK signaling pathway has been implicated in the development and progression of many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

SPAG9 is a key regulator of the CJK signaling pathway and has been shown to play a critical role in the development and progression of many diseases. SPAG9 is associated with the CJK signaling pathway because it is a critical regulator of the activity of the CJK protein, which is involved in the regulation of many cellular processes, including cell growth, apoptosis, and angiogenesis.

SPAG9 is also associated with the development and progression of many diseases because it is a critical regulator of the activity of the T-cell receptor (TCR), which is a protein that is involved in the regulation of adaptive immunity. The TCR is a critical regulator of T-cell development and function and is involved in the development and progression of many diseases, including cancer.

SPAG9 is a potential drug target because it is associated with the development and progression of many diseases and is involved in the regulation of the CJK and TCR signaling pathways, which are involved in the development and progression of many diseases. Additionally, SPAG9 has been shown to be overexpressed in many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders, which suggests that it may be a useful biomarker for these diseases.

SPAG9 is also a potential biomarker for many diseases because it is associated with the development and progression of many diseases and is involved in the regulation of the CJK and TCR signaling pathways, which are involved in the development and progression of many diseases. Additionally, SPAG9 has been shown to be overexpressed in many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders, which suggests that it may be a useful biomarker for these diseases.

Conclusion

SPAG9 is a non-coding RNA molecule that is associated with the c-Jun NH2-terminal kinase (CJK) and the T-cell receptor (TCR) signaling pathways. SPAG9 is a potential drug target and biomarker for the development and progression of many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of SPAG9 in the development and progression of these diseases and to develop effective therapies that target SPAG9.

Protein Name: Sperm Associated Antigen 9

Functions: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module (PubMed:14743216). Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex (PubMed:29146937). Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking (By similarity)

The "SPAG9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPAG9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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