Target Name: ACY1
NCBI ID: G95
Review Report on ACY1 Target / Biomarker Content of Review Report on ACY1 Target / Biomarker
ACY1
Other Name(s): ACY-1 | Aminoacylase 1, transcript variant 1 | ACY1_HUMAN | aminoacylase 1 | ACY1D | ACY1 variant 1 | ACYLASE | Aminoacylase-1 (isoform a) | epididymis secretory protein Li 5 | HEL-S-5 | acylase | N-acyl-L-amino-acid amidohydrolase | Aminoacylase-1

ACY1: A Potential Drug Target for Diabetes, Obesity and Cancer

ACY1 (ACY-1), a protein that belongs to the insulin secretion Signaling (ISS) pathway, has been identified as a potential drug target or biomarker for the treatment of various diseases, including type 2 diabetes, obesity, and cancer. The ISS pathway is a critical signaling pathway that regulates the production and release of insulin, a hormone that plays a crucial role in regulating blood sugar levels. The ACY1 protein has been shown to regulate insulin secretion and has been linked to the development and progression of various diseases.

The ACY1 protein is a 21-kDa protein that is expressed in various tissues, including pancreas, fat tissue, and muscle tissue. It is a key component of the ISS pathway and has been shown to regulate the production and release of insulin. The ISS pathway is a complex signaling pathway that involves multiple proteins and is responsible for regulating the production and release of insulin. The ACY1 protein is one of the key proteins that regulates insulin secretion.

Studies have shown that the ACY1 protein is involved in the regulation of insulin secretion in various tissues. For example, researchers have shown that the ACY1 protein is involved in the regulation of insulin secretion in pancreatic beta cells, which are responsible for producing insulin. Other studies have shown that the ACY1 protein is involved in the regulation of insulin secretion in fat tissue, which is important for the treatment of obesity.

In addition to its role in insulin secretion, the ACY1 protein has also been shown to be involved in the regulation of various cellular processes, including inflammation and cellular signaling. For example, studies have shown that the ACY1 protein is involved in the regulation of inflammation in various tissues, including muscle tissue and pancreatic tissue.

The potential drug target or biomarker status of the ACY1 protein has led to a great deal of interest and research in recent years. Studies have shown that blocking the ACY1 protein using small interfering RNA (siRNA) or using antibodies can lead to the regression of various diseases, including type 2 diabetes, obesity, and cancer. For example, researchers have shown that inhibiting the ACY1 protein using siRNA can lead to the regression of obesity in mice.

In addition to its potential therapeutic uses, the ACY1 protein has also been shown to be a useful biomarker for the diagnosis and monitoring of various diseases. For example, studies have shown that the ACY1 protein is involved in the regulation of insulin secretion, which can be used as a biomarker for the diagnosis and monitoring of type 2 diabetes. Other studies have shown that the ACY1 protein is involved in the regulation of inflammation, which can be used as a biomarker for the diagnosis and monitoring of various inflammatory diseases.

Overall, the ACY1 protein has a great deal of potential as a drug target or biomarker for the treatment of various diseases. Further research is needed to fully understand its role in the ISS pathway and its potential therapeutic uses.

Protein Name: Aminoacylase 1

Functions: Catalyzes the hydrolysis of N-acetylated amino acids to acetate and free amino acids

The "ACY1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ACY1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ACY3 | Acyl-CoA dehydrogenase (ACAD) | Acyl-CoA Synthetase Short-Chain | ACYP1 | ACYP2 | ADA | ADA2 | ADA2A-containing complex (ATAC) | ADAD1 | ADAD2 | ADAL | ADAM10 | ADAM11 | ADAM12 | ADAM15 | ADAM17 | ADAM18 | ADAM19 | ADAM1A | ADAM1B | ADAM2 | ADAM20 | ADAM20P1 | ADAM21 | ADAM21P1 | ADAM22 | ADAM23 | ADAM28 | ADAM29 | ADAM30 | ADAM32 | ADAM33 | ADAM3A | ADAM5 | ADAM6 | ADAM7 | ADAM7-AS1 | ADAM7-AS2 | ADAM8 | ADAM9 | ADAMDEC1 | ADAMTS1 | ADAMTS10 | ADAMTS12 | ADAMTS13 | ADAMTS14 | ADAMTS15 | ADAMTS16 | ADAMTS16-DT | ADAMTS17 | ADAMTS18 | ADAMTS19 | ADAMTS2 | ADAMTS20 | ADAMTS3 | ADAMTS4 | ADAMTS5 | ADAMTS6 | ADAMTS7 | ADAMTS7P1 | ADAMTS7P3 | ADAMTS7P4 | ADAMTS8 | ADAMTS9 | ADAMTS9-AS1 | ADAMTS9-AS2 | ADAMTSL1 | ADAMTSL2 | ADAMTSL3 | ADAMTSL4 | ADAMTSL4-AS1 | ADAMTSL5 | ADAP1 | ADAP2 | Adapter protein complex 5 | Adaptor-related protein complex 1 | Adaptor-related protein complex 2 | Adaptor-Related Protein Complex 3 | Adaptor-related protein complex 4 | ADAR | ADARB1 | ADARB2 | ADARB2-AS1 | ADAT1 | ADAT2 | ADAT3 | ADCK1 | ADCK2 | ADCK5 | ADCY1 | ADCY10 | ADCY10P1 | ADCY2 | ADCY3 | ADCY4 | ADCY5 | ADCY6 | ADCY7 | ADCY8 | ADCY9