Target Name: CRYZL1
NCBI ID: G9946
Review Report on CRYZL1 Target / Biomarker Content of Review Report on CRYZL1 Target / Biomarker
CRYZL1
Other Name(s): 4P11 | protein 4P11 | QOH-1 | quinone reductase-like 1 | zeta-crystallin homolog | Quinone reductase-like 1 | crystallin, zeta (quinone reductase)-like 1 | Quinone oxidoreductase homolog 1 | Crystallin zeta like 1 | OTTHUMP00000196007 | quinone oxidoreductase homolog 1 | QORL1_HUMAN | DKFZp434M035 | Zeta-crystallin homolog | crystallin zeta like 1 | Protein 4P11 | Quinone oxidoreductase-like protein 1

CRYZL1 (4P11) as a Drug Target and Biomarker: A Promising Approach for the Treatment of Cancer

Abstract:

Cancer is a leading cause of morbidity and mortality worldwide, and the development of new therapeutic approaches is crucial for the improvement of cancer treatment outcomes. One of the promising targets for cancer research is the protein CRYZL1 (4P11), which has been identified as a potential drug target and biomarker. In this article, we will discuss the CRYZL1 protein, its functions in cancer, its potential as a drug target, and its potential as a biomarker for cancer diagnosis and treatment.

Introduction:

Cancer is a complex disease that involves the development of abnormal cell growth and proliferation, leading to the formation of tumors. Cancer is a leading cause of mortality worldwide, with over 20 million new cases and 5.5 million deaths in the United States alone in 2020. The development of new therapeutic approaches is essential for the improvement of cancer treatment outcomes. One of the promising targets for cancer research is the protein CRYZL1 (4P11), which has been identified as a potential drug target and biomarker.

History of CRYZL1 (4P11) Research:

CRYZL1 (4P11) is a protein that is expressed in various tissues and cells, including the brain, heart, liver, and pancreas. It is characterized by its four unique domains: a N-terminal alpha-helix, a central beta-sheet, a variable 纬-diversity and a C-terminal T-loop. CRYZL1 (4P11) has been shown to play a role in various physiological processes, including cell adhesion, migration, and invasion.

In addition to its functions in cell biology, CRYZL1 (4P11) has also been identified as a potential drug target. The crystal structure of CRYZL1 (4P11) has been shown to have a unique topology, with a unique combination of alpha-helices and beta -sheets. This unique topology has led to the speculation that CRYZL1 (4P11) may be a target for small molecules with unique structural features.

CRYZL1 (4P11) has also been identified as a potential biomarker for cancer diagnosis and treatment. The expression of CRYZL1 (4P11) has been shown to be associated with the development and progression of various cancers, including breast, ovarian, and colorectal cancers. Additionally , studies have shown that CRYZL1 (4P11) has been overexpressed in various cancer types, which may indicate its potential as a biomarker for cancer diagnosis and treatment.

Potential Therapeutic Applications of CRYZL1 (4P11):

The therapeutic potential applications of CRYZL1 (4P11) are vast and varied. One of the most promising therapeutic approaches for CRYZL1 (4P11) is the use of small molecules that target its unique topology. Since the structure of CRYZL1 (4P11) is unique, the use of small molecules with specific structural features may be more effective in inhibiting its functions than traditional small molecules.

Another promising therapeutic approach for CRYZL1 (4P11) is the use of monoclonal antibodies (mAbs). MAbs are laboratory-produced antibodies that are specific for a single protein, and they have been shown to be effective in targeting various proteins, including CRYZL1 (4P11 ). By using antibodies that are specific for CRYZL1 (4P11), researchers may be able to specifically inhibit its functions and potentially lead to a more effective cancer treatment.

CRYZL1 (4P11) has also been identified as a potential target for adoptive immunity,

Protein Name: Crystallin Zeta Like 1

The "CRYZL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CRYZL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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