Target Name: MVP
NCBI ID: G9961
Review Report on MVP Target / Biomarker Content of Review Report on MVP Target / Biomarker
MVP
Other Name(s): MVP_HUMAN | Major vault protein, transcript variant 2 | MVP variant 2 | major vault protein | LRP | OTTHUMP00000045913 | Major vault protein, transcript variant 1 | Lung resistance-related protein | testicular secretory protein Li 30 | Major vault protein (isoform 1) | VAULT1 | Major vault protein | MVP variant 1 | lung resistance-related protein

A Comprehensive Analysis of the Potential Drug Target and Biomarker MVP Human

Abstract:

The human biomarker MVP (MVP_HUMAN) has gained significant attention due to its potential as a drug target. This protein is expressed in various tissues and cells of the human body and has been associated with various diseases, including cancer. In this article, we will discuss the biology and potential drug targets of MVP_HUMAN, as well as its potential as a biomarker for disease diagnosis and treatment.

Introduction:

MVP_HUMAN is a protein that is expressed in various tissues and cells of the human body. It has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The potential drug targets for MVP_HUMAN have been identified, and several studies have demonstrated its potential in preclinical models. In this article, we will provide a comprehensive analysis of MVP_HUMAN, including its biology, potential drug targets, and potential as a biomarker for disease diagnosis and treatment.

Biology and Function:

MVP_HUMAN is a 21-kDa protein that is expressed in various tissues and cells of the human body, including the brain, muscle, heart, liver, and kidney. It is a member of the protamine superfamily and is characterized by its N-terminal alpha -helix, a conserved region of 12 amino acids, and a C-terminal T-loop. MVP_HUMAN has been shown to play a role in various physiological processes, including cell signaling, DNA replication, and cell survival.

In addition to its role in cell signaling, MVP_HUMAN has also been implicated in the development and progression of various diseases. For example, it has been shown to be overexpressed in various cancer tissues and to contribute to cancer cell invasiveness and metastasis. In neurodegenerative diseases , MVP_HUMAN has been implicated in the pathophysiology of various neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease.

Potential Drug Targets:

MVP_HUMAN has several potential drug targets due to its unique biology and expression pattern in various tissues and cells of the human body. One of the most promising drug targets for MVP_HUMAN is the PI3K/Akt signaling pathway, which is a central regulator of cell signaling. This pathway is involved in various cellular processes, including cell survival, angiogenesis, and inflammation.

MVP_HUMAN has been shown to interact with the protein PIK3K, which is a key component of the PI3K/Akt signaling pathway. By modulating the activity of PIK3K, MVP_HUMAN has been shown to influence various cellular processes, including cell proliferation, migration, and invasion. Therefore, targeting MVP_HUMAN with drugs that inhibit PI3K/Akt signaling pathway could be an effective strategy for treating various diseases, including cancer and neurodegenerative disorders.

In addition to its role in cell signaling, MVP_HUMAN has also been implicated in the development and progression of various diseases. For example, it has been shown to contribute to the pathophysiology of cancer, neurodegenerative diseases, and autoimmune disorders. Therefore, targeting MVP_HUMAN with drugs that modulate its expression and activity could be an effective strategy for treating these diseases.

Potential as a Biomarker:

MVP_HUMAN has several potential biomarkers that could be used for disease diagnosis and treatment. One of the most promising biomarkers for MVP_HUMAN is its ability to be targeted by small molecules, such as drugs that inhibit its expression or activity. Therefore, using techniques such as high -throughput screening and bioinformatics analysis could identify small molecules that are effective in targeting MVP_HUMAN and its associated diseases.

Another potential biomarker for MVP_HUMAN is its expression pattern in various tissues and cells of the human body. By analyzing the expression patterns of MVP_HUMAN in different tissues and cells, researchers could identify potential biomarkers for disease diagnosis and treatment. For example, if MVP_HUMAN is overexpressed in certain tissues or cells, it could be an indicator of disease progression or a potential target for therapy.

Conclusion:

MVP_HUMAN is a protein that is expressed in various tissues and cells of the human body and has been associated with various diseases, including cancer. Its potential as a drug target and biomarker has been identified and demonstrated in preclinical models. Further research is needed to fully understand the biology and function of MVP_HUMAN and its potential as a drug target and biomarker for disease diagnosis and treatment.

Protein Name: Major Vault Protein

Functions: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases

The "MVP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MVP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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