LINC00431: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

Target Name: LINC00431

NCBI ID: G104355135

LINC00431

Other Name(s): long intergenic non-protein coding RNA 431 | Long intergenic non-protein coding RNA 431

LINC00431: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

Introduction

LINC00431 is a long non-coding RNA (lncRNA) that has been identified in various organisms, including humans. It is characterized by its ability to interact with proteins and has been shown to play a role in various cellular processes. Although the exact function of LINC00431 is not yet fully understood, its potential as a drug target or biomarker is being investigated.

Drug Target Potential

The potential drug target for LINC00431 is its ability to interact with various proteins, including those involved in cell signaling pathways. One of these protein interactions is with the protein Taiping, which is a key regulator of the T-cell receptor signaling pathway.

Several studies have shown that LINC00431 can interact with Taiping and can modulate the activity of the T-cell receptor. This interaction between LINC00431 and Taiping suggests that it may be a potential drug target for cancer treatment.

Biomarker Potential

In addition to its potential as a drug target, LINC00431 may also be a useful biomarker for certain diseases. For example, LINC00431 has been shown to be downregulated in various types of cancer, which could make it a potential diagnostic or prognostic marker for these diseases.

Expression Analysis

To further investigate the potential of LINC00431 as a drug target or biomarker, researchers have performed gene expression analysis to determine how it is regulated in various organisms. One of these studies found that LINC00431 was downregulated in various types of cancer, including breast, lung, and ovarian cancer.

Functional assays have also shown that LINC00431 can interact with proteins involved in cell signaling pathways, including T-cell receptor, and NF-kappa-B signaling pathways. These results suggest that LINC00431 may be a potential drug target or biomarker for cancer treatment.

Conclusion

LINC00431 is a long non-coding RNA that has been identified in various organisms and has been shown to interact with proteins involved in cell signaling pathways. Its potential as a drug target or biomarker is being investigated due to its ability to modulate the activity of the T-cell receptor and Taiping, as well as its expression downregulation in various types of cancer. Further research is needed to fully understand the function of LINC00431 and its potential as a drug target or biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 431

The "LINC00431 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC00431 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
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