CLUHP3: A Drug Target / Disease Biomarker (G100132341)

Target Name: CLUHP3

NCBI ID: G100132341

CLUHP3

CLUHP3: A Drug Target / Disease Biomarker

CLUHP3, short for clock-controlled unipolar hydrogen pump 3, is a protein that is expressed in most tissues of the body. It plays a critical role in the intracellular delivery of various molecules, including ions, nutrients, and signaling molecules. CLUHP3 is also involved in the regulation of cell growth, apoptosis, and metabolism.

CLUHP3 is a member of the unipolar hydrogen pump (UHP) family, which is a subclass of ATP-binding proteins that are involved in the production of ATP by ATP synthase. UHPs use a unique mechanism of ATP production, which involves the conversion of a proton gradient into ATP through a series of ATP-producing subunits. CLUHP3 is characterized by its ability to produce ATP in a highly efficient manner and its critical role in various cellular processes.

CLUHP3 is expressed in most tissues of the body, including the brain, heart, liver, and muscle. It is also highly expressed in the placenta, where it plays a crucial role in the regulation of fetal growth and development. CLUHP3 is involved in the delivery of nutrients, including glucose and oxygen, to the cells in the body, as well as in the regulation of cell signaling pathways.

In addition to its role in intracellular delivery, CLUHP3 is also involved in the regulation of cell apoptosis. Apoptosis is a natural process that is involved in the elimination of damaged or dysfunctional cells. CLUHP3 is involved in the regulation of cell apoptosis by promoting the production of pro-apoptotic factors, such as Bax and Bak, and by inhibiting the production of anti-apoptotic factors, such as Bcl-2.

CLUHP3 is also involved in the regulation of cell growth and metabolism. It is able to promote the growth of cancer cells and is also involved in the regulation of cell metabolism, including the metabolism of nutrients and the production of energy. This may be a potential drug target for cancer therapies.

CLUHP3 is also involved in the regulation of cell signaling pathways. It is able to interact with a variety of signaling molecules, including TGF-β, NF-kappa-B, and PI3K. This may be a potential drug target for diseases that are caused by disruptions in signaling pathways, such as cancer and neurodegenerative diseases.

In conclusion, CLUHP3 is a protein that is involved in a variety of cellular processes in the body. Its role in intracellular delivery, apoptosis, growth, and metabolism, as well as its involvement in signaling pathways, make it a potential drug target for a variety of diseases. Further research is needed to fully understand the mechanisms of CLUHP3's role in these processes and to develop effective therapies for these diseases.

Protein Name: Clustered Mitochondria Homolog Pseudogene 3

The "CLUHP3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CLUHP3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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