Cholestasis
About the Disease
Cholestasis, also known as obstruction of bile duct, is related to cholestasis, intrahepatic, of pregnancy 3 and cholestasis, benign recurrent intrahepatic, 2, and has symptoms including icterus and jaundice (not of newborn). An important gene associated with Cholestasis is USP53 (Ubiquitin Specific Peptidase 53), and among its related pathways/superpathways are Metabolism and Nuclear receptors meta-pathway. The drugs Lactulose and Sorbitol have been mentioned in the context of this disorder. Affiliated tissues include liver, pancreas and kidney, and related phenotypes are no effect and no effect
Common Targets
G7040 | G151306 | G5142 | Ribonucleoside-diphosphate reductase | G1581 | G284086 | G5465 | G94160 | G4358 | G80339 | G8824 | G55107 | G5244 | G1268 | G5468 | G113220 | G7082 | G5205 | G54532 | G7124 | P6320 | G56652 | G3105 | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | G6718 | G8856 | G5467 | G9429 | G836 | G26276 | G182 | G9971 | G6554 | G2101 | G5428 | G540 | G407018 | G345275 | Caspase (nonspecified subtype) | G10165 | G51473 | G6555 | G6888 | G1080 | G4853 | G54658 | G80270 | P16740 | G4363 | G5406 | G8647 | G4864 | G114548 | G4129 | G6928 | G4645 | P6058 | G6097 | G9414
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Cholestasis, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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