Target Name: MICOS13
NCBI ID: G125988
Review Report on MICOS13 Target / Biomarker Content of Review Report on MICOS13 Target / Biomarker
MICOS13
Other Name(s): Protein QIL1 | MIC13 | mitochondrial contact site and cristae organizing system subunit 13 | C19orf70 | Protein P117 | MIC13_HUMAN | MICOS complex subunit MIC13 (isoform 2) | MICOS complex subunit MIC13 | protein QIL1 | QIL1 | Mitochondrial contact site and cristae organizing system subunit 13, transcript variant 2 | P117 | MICOS13 variant 2 | MIC12

MICOS13: A Protein Involved in Pain and Neuroinflammation

MICOS13, also known as Protein QIL1, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Q-type ion channels, which are a family of transmembrane proteins that play a crucial role in ion transport and signaling in various biological systems.

One of the unique features of MICOS13 is its ability to form a pore, or channel, in the cell membrane. This pore allows the protein to regulate the flow of ions and molecules through the membrane, which is a critical function in many cellular processes, including signaling, neurotransmission, and ion homeostasis.

MICOS13 is also known for its role in the regulation of pain perception and neuroinflammation. Studies have shown that MICOS13 is involved in the production of pain signals, and that it may also contribute to the persistent pain that can be associated with certain neurological conditions.

In addition to its role in pain regulation, MICOS13 is also a potential drug target for several diseases. For example, MICOS13 has been shown to be involved in the development and progression of several types of cancer, including neuro cancer. Additionally, the regulation of MICOS13 has been implicated in a number of diseases, including obesity, diabetes, and cardiovascular disease.

Despite these promising findings, much more research is needed to fully understand the role of MICOS13 in disease. In particular, researchers are in need of better methods for studying the precise function of MICOS13 in different biological systems, as well as methods for blocking or modulating its activity.

In conclusion, MICOS13 is a protein that is expressed in a variety of tissues and is involved in a wide range of cellular processes, including ion transport, signaling, and pain regulation. Its unique ability to form pores in the cell membrane makes it a potential drug target for several diseases, and its role in pain and neuroinflammation suggests that it may also be a valuable biomarker for tracking these conditions. Further research is needed to fully understand the function of MICOS13 and its potential as a drug target.

Protein Name: Mitochondrial Contact Site And Cristae Organizing System Subunit 13

Functions: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MICOS10/MIC10 into the MICOS complex

The "MICOS13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MICOS13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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