OSCAR: A Potential Drug Target for Osteoporosis and MS (G126014)
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OSCAR: A Potential Drug Target for Osteoporosis and MS
OSCAR (Osteoclast-associated immunoglobulin-like receptor (isoform 1)) is a protein that is expressed in osteoclasts, which are cells that are part of the immune system and are responsible for breaking down bone tissue. OSCAR is a member of the immunoglobulin superfamily and is characterized by the presence of a nucleotide-binding oligomerization domain (NOD) and a constant region.
The OSCAR gene was identified in the late 1990s as a potential drug target in the field of osteoporosis. Osteoporosis is a condition in which the bones become weak and fragile due to a loss of bone mass. It is a leading cause of hip fractures in older adults and is associated with a decreased quality of life.
OSCAR is a negative regulator of the immune response and has been shown to play a role in the regulation of cellular immunity. OSCAR is also involved in the regulation of inflammation and has been shown to have anti-inflammatory effects.
In addition to its potential therapeutic applications, OSCAR has also been shown to be a valuable biomarker for the diagnosis and monitoring of osteoporosis. OSCAR levels have been found to be decreased in individuals with osteoporosis and have been used as a diagnostic marker for this condition.
OSCAR is also a potential drug target for other diseases. For example, OSCAR has been shown to be involved in the development and progression of multiple sclerosis (MS), a chronic and debilitating disease that affects the central nervous system.
In addition to its potential therapeutic applications, OSCAR has also been shown to have potential as a biomarker for monitoring the effectiveness of MS treatments. OSCAR levels have been found to be decreased in individuals with MS and have been used as a marker for the effectiveness of disease-modifying therapies.
OSCAR is a protein that has the potential to revolutionize our understanding of osteoporosis and multiple sclerosis. Further research is needed to fully understand the role of OSCAR in these diseases and to develop effective treatments.
Protein Name: Osteoclast Associated Ig-like Receptor
Functions: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation
The "OSCAR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OSCAR comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
OSCP1 | OSER1 | OSER1-DT | OSGEP | OSGEPL1 | OSGEPL1-AS1 | OSGIN1 | OSGIN2 | OSM | OSMR | OSMR-DT | OSR1 | OSR2 | OST4 | OSTC | OSTCP1 | OSTF1 | OSTF1P1 | OSTM1 | OSTM1-AS1 | OSTN | OSTN-AS1 | OTC | OTOA | OTOAP1 | OTOF | OTOG | OTOGL | OTOL1 | OTOP1 | OTOP2 | OTOP3 | OTOR | OTOS | OTP | OTUB1 | OTUB2 | OTUD1 | OTUD3 | OTUD4 | OTUD5 | OTUD6A | OTUD6B | OTUD6B-AS1 | OTUD7A | OTUD7B | OTULIN | OTULINL | OTX1 | OTX2 | OTX2-AS1 | OVAAL | OVCA2 | OVCH1 | OVCH1-AS1 | OVCH2 | OVGP1 | OVOL1 | OVOL1-AS1 | OVOL2 | OVOL3 | OVOS2 | OXA1L | OXA1L-DT | OXCT1 | OXCT1-AS1 | OXCT2 | OXCT2P1 | OXER1 | OXGR1 | OXLD1 | OXNAD1 | OXR1 | OXSM | OXSR1 | OXT | OXTR | Oxysterol-binding protein | Oxysterols receptor LXR | P2RX1 | P2RX2 | P2RX3 | P2RX4 | P2RX5 | P2RX5-TAX1BP3 | P2RX6 | P2RX6P | P2RX7 | P2RY1 | P2RY10 | P2RY10BP | P2RY11 | P2RY12 | P2RY13 | P2RY14 | P2RY2 | P2RY4 | P2RY6 | P2RY8 | P2X Receptor