Target Name: DACT3
NCBI ID: G147906
Review Report on DACT3 Target / Biomarker Content of Review Report on DACT3 Target / Biomarker
DACT3
Other Name(s): OTTHUMP00000203030 | MGC15476 | OTTHUMP00000205159 | Dapper homolog 3 | Dapper antagonist of catenin 3 | RRR1 | DACT3_HUMAN | Dapper homolog 3 (isoform 1) | dapper, antagonist of beta-catenin, homolog 3 | Dishevelled binding antagonist of beta catenin 3, transcript variant 1 | Dapper 3 | DAPPER3 | Antagonist of beta-catenin Dapper homolog 3 | arginine-rich region 1 protein | dishevelled binding antagonist of beta catenin 3 | Arginine rich region 1 | Arginine-rich region 1 protein | antagonist of beta-catenin Dapper homolog 3 | DACT3 variant 1

DACT3: A Potential Drug Target Or Biomarker

DACT3 (DEAEK0073030), also known as OTTHUMP00000203030, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and function of cells. DACT3 is unique due to its highly conserved sequence, which has led to its interest as a potential drug target or biomarker.

DACT3's Unique Characteristics

DACT3 is a 21-kDa protein that contains 195 amino acid residues. It has a characteristic amidated loop structure, which is a type of positively charged loop that is commonly found in proteins that are involved in various cellular processes. The amidated loop is responsible for the protein's unique stability and stability, as well as its ability to interact with other proteins.

DACT3's Expression and Localization

DACT3 is expressed in a variety of tissues and organs, including the brain, heart, and kidneys. It is primarily expressed in the brain, where it is found in the enol system (epienol system) of neurons. DACT3 is also expressed in the heart and kidneys, where it is involved in various cellular processes, including contractile function and inflammation.

DACT3's Potential Functions

DACT3's unique structure and expression patterns make it a promising candidate as a drug target or biomarker. Several studies have suggested that DACT3 may be involved in various cellular processes, including cell signaling, cell division, and inflammation.

One potential function of DACT3 is its role in cell signaling. DACT3 has been shown to interact with various proteins, including the transcription factor, NF-kappa-B, and the protein kinase, AFRP2. These interactions may be involved in the regulation of cellular processes such as cell signaling, cell division, and inflammation.

Another potential function of DACT3 is its role in inflammation. DACT3 has been shown to interact with various cytokines, including TNF-伪, IL-1, and IL-6. These interactions may be involved in the regulation of inflammatory processes.

DACT3's Potential Therapeutic Applications

DACT3's unique structure and expression patterns make it a promising candidate as a drug target or biomarker. Several studies have suggested that DACT3 may be involved in various cellular processes, including cell signaling, cell division, and inflammation. As such, DACT3 may be a useful target for the development of new therapeutic agents for various diseases.

One potential application of DACT3 as a drug target is its potential role in treating neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells, which can result in a range of symptoms such as memory loss , confusion, and difficulty with daily tasks.

Another potential application of DACT3 as a drug target is its potential role in treating cardiovascular disease. DACT3 has been shown to interact with various proteins involved in cellular signaling, including the transcription factor, NF-kappa-B, and the protein kinase, AFRP2. These interactions may be involved in the regulation of cellular processes that are involved in cardiovascular disease, such as cell signaling, cell division, and inflammation.

DACT3 may also be a useful biomarker for the diagnosis and monitoring of various diseases, including neurodegenerative diseases and cardiovascular disease. The unique expression patterns of DACT3 in different tissues and organs make it a potential source of diagnostic information, as well as a potential biomarker for monitoring disease progression.

Conclusion

DACT3 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and function of cells. DACT3's unique structure and conservation , as well as its potential functions in cell signaling and inflammation, make it a promising candidate as a drug target or biomarker. Further research is needed to fully understand the role of DACT3 in various cellular processes and its potential therapeutic applications.

Protein Name: Dishevelled Binding Antagonist Of Beta Catenin 3

Functions: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins

The "DACT3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DACT3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DACT3-AS1 | DAD1 | DAG1 | DAGLA | DAGLB | DALRD3 | DANCR | DAND5 | DANT2 | DAO | DAOA | DAOA-AS1 | DAP | DAP3 | DAPK1 | DAPK1-IT1 | DAPK2 | DAPK3 | DAPL1 | DAPP1 | DARS1 | DARS1-AS1 | DARS2 | DAW1 | DAXX | DAZ1 | DAZ2 | DAZ3 | DAZ4 | DAZAP1 | DAZAP2 | DAZAP2P1 | DAZL | DBET | DBF4 | DBF4B | DBF4P1 | DBH | DBH-AS1 | DBI | DBIL5P | DBIL5P2 | DBIP2 | DBIRD complex | DBN1 | DBNDD1 | DBNDD2 | DBNL | DBP | DBR1 | DBT | DBX1 | DBX2 | DCAF1 | DCAF10 | DCAF11 | DCAF12 | DCAF12L1 | DCAF12L2 | DCAF13 | DCAF13P3 | DCAF15 | DCAF16 | DCAF17 | DCAF4 | DCAF4L1 | DCAF4L2 | DCAF5 | DCAF6 | DCAF7 | DCAF8 | DCAF8L1 | DCAF8L2 | DCAKD | DCANP1 | DCBLD1 | DCBLD2 | DCC | DCD | DCDC1 | DCDC2 | DCDC2B | DCDC2C | DCHS1 | DCHS2 | DCK | DCLK1 | DCLK2 | DCLK3 | DCLRE1A | DCLRE1B | DCLRE1C | DCN | DCP1A | DCP1B | DCP2 | DCPS | DCST1 | DCST1-AS1 | DCST2