Target Name: DCAF6
NCBI ID: G55827
Review Report on DCAF6 Target / Biomarker Content of Review Report on DCAF6 Target / Biomarker
DCAF6
Other Name(s): androgen receptor complex-associated protein | DDB1- and CUL4-associated factor 6 (isoform d) | IQWD1 | Nuclear receptor interaction protein | IQ motif and WD repeat-containing protein 1 | DCAF6_HUMAN | RP4-745I14.1 | FLJ23798 | DCAF6 variant 3 | MSTP055 | DDB1 and CUL4 associated factor 6, transcript variant 4 | DDB1- and CUL4-associated factor 6 | NRIP | ARCAP | PC326 | 1200006M05Rik | Androgen receptor complex-associated protein | DDB1 and CUL4 associated factor 6 | DDB1 and CUL4 associated factor 6, transcript variant 3 | nuclear receptor interaction protein | DDB1- and CUL4-associated factor 6 (isoform c) | DCAF6 variant 4 | IQ motif and WD repeats 1

DCAF6: Key Regulator of Androgen Signaling

The DCAF6 protein is a key regulator of androgen signaling in the body. It is a protein that is expressed in a variety of tissues, including the brain, testes, and pancreas, and is involved in the signaling of androgens, such as testosterone, to various tissues and organs.

One of the key functions of DCAF6 is to regulate the androgen receptor (AR), which is a protein that is responsible for mediating the effects of androgens. The AR is a transmembrane protein that is composed of two distinct subunits: the AR伪 subunit and the AR尾 subunit. The AR伪 subunit is the protein that is directly activated by androgens, while the AR尾 subunit is a negative regulator that helps to keep the AR伪 subunit in a inhibited state.

DCAF6 is highly conserved, with a sequence of 215 amino acids. It is found in a variety of organisms, including bacteria, archaea, and eukaryotes. It is expressed in many different tissues and organs, including the brain, testes, and pancreas.

DCAF6 is involved in the regulation of a wide range of biological processes, including sexual development and behavior, aggression, and metabolism. It is also involved in the development and progression of various diseases, including cancer.

One of the key functions of DCAF6 is to regulate the AR. The AR is a transmembrane protein that is composed of two distinct subunits: the AR伪 subunit and the AR尾 subunit. The AR伪 subunit is the protein that is directly activated by androgens, while the AR尾 subunit is a negative regulator that helps to keep the AR伪 subunit in a inhibited state.

DCAF6 is highly conserved, with a sequence of 215 amino acids. It is found in a variety of organisms, including bacteria, archaea, and eukaryotes. It is expressed in many different tissues and organs, including the brain, testes, and pancreas.

DCAF6 is involved in the regulation of a wide range of biological processes, including sexual development and behavior, aggression, and metabolism. It is also involved in the development and progression of various diseases, including cancer.

One of the key functions of DCAF6 is to regulate the AR. The AR is a transmembrane protein that is composed of two distinct subunits: the AR伪 subunit and the AR尾 subunit. The AR伪 subunit is the protein that is directly activated by androgens, while the AR尾 subunit is a negative regulator that helps to keep the AR伪 subunit in a inhibited state.

DCAF6 is highly conserved, with a sequence of 215 amino acids. It is found in a variety of organisms, including bacteria, archaea, and eukaryotes. It is expressed in many different tissues and organs, including the brain, testes, and pancreas.

DCAF6 is involved in the regulation of a wide range of biological processes, including sexual development and behavior, aggression, and metabolism. It is also involved in the development and progression of various diseases, including cancer.

In addition to its role in regulating the AR, DCAF6 is also involved in the regulation of a variety of other proteins and factors. For example, it is known to be involved in the regulation of the androgen receptor-regulated gene expression (AR-REP), which is a complex that is responsible for the regulation of androgen signaling.

DCAF6 is also involved in the regulation of the sex hormone-regulated gene expression (SHRG), which is a complex that is responsible for the regulation of the expression of genes that are involved in sexual behavior and development.

In addition to its role in regulating the AR and SHRG, DCAF6 is also involved in the regulation of a variety of other proteins and factors. For example, it is known to be involved in the regulation of the

Protein Name: DDB1 And CUL4 Associated Factor 6

Functions: Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex

The "DCAF6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DCAF6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DCAF7 | DCAF8 | DCAF8L1 | DCAF8L2 | DCAKD | DCANP1 | DCBLD1 | DCBLD2 | DCC | DCD | DCDC1 | DCDC2 | DCDC2B | DCDC2C | DCHS1 | DCHS2 | DCK | DCLK1 | DCLK2 | DCLK3 | DCLRE1A | DCLRE1B | DCLRE1C | DCN | DCP1A | DCP1B | DCP2 | DCPS | DCST1 | DCST1-AS1 | DCST2 | DCSTAMP | DCT | DCTD | DCTN1 | DCTN1-AS1 | DCTN2 | DCTN3 | DCTN4 | DCTN5 | DCTN6 | DCTPP1 | DCUN1D1 | DCUN1D2 | DCUN1D3 | DCUN1D4 | DCUN1D5 | DCX | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | DCX DET1-COP1 ubiquitin ligase complex | DCX(DCAF15) E3 protein ligase complex | DCXR | DDA1 | DDAH1 | DDAH2 | DDB1 | DDB2 | DDC | DDC-AS1 | DDD core complex | DDHD1 | DDHD2 | DDI1 | DDI2 | DDIAS | DDIT3 | DDIT4 | DDIT4L | DDN | DDO | DDOST | DDR1 | DDR2 | DDRGK1 | DDT | DDTL | DDX1 | DDX10 | DDX11 | DDX11-AS1 | DDX11L1 | DDX11L10 | DDX11L2 | DDX11L8 | DDX11L9 | DDX12P | DDX17 | DDX18 | DDX18P1 | DDX19A | DDX19A-DT | DDX19B | DDX20 | DDX21 | DDX23 | DDX24 | DDX25 | DDX27 | DDX28 | DDX31