ADRB2: A G Protein-Coupled Receptor and Potential Drug Target

Target Name: ADRB2

NCBI ID: G154

ADRB2

ADRB2: A G Protein-Coupled Receptor and Potential Drug Target

The beta-2 adrenoreceptor (ADRB2) is a G protein-coupled receptor that is expressed in many tissues throughout the body. It plays a crucial role in the regulation of cardiovascular, respiratory, and neurochemical responses to the body's environment. The ADRB2 is a potential drug target and has been identified as a biomarker for various diseases, including cardiovascular disease, diabetes, and neurodegenerative disorders.

The ADRB2 is a member of the G protein-coupled receptor family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. The ADRB2 is characterized by its long, N-terminal extracellular domain, which contains a unique farnesylated cysteine residue. This cysteine residue is known as a lysine-rich region (LRR) and is involved in the formation of the ADRB2 complex.

The ADRB2 is expressed in many tissues throughout the body, including the heart, lungs, brain, and kidneys. It is involved in the regulation of various physiological processes, including cardiovascular, respiratory, and neurochemical responses to the body's environment. For example, the ADRB2 is involved in the regulation of heart rate and blood pressure, and is thought to play a role in the development of hypertension. It is also involved in the regulation of breathing patterns and is thought to contribute to the development of sleep disorders.

The ADRB2 is a potential drug target because of its involvement in various diseases. For example, the ADRB2 is known to be involved in the development and progression of cardiovascular disease, and is thought to play a role in the regulation of blood pressure. The ADRB2 is also involved in the regulation of diabetes, and is thought to contribute to the development of neurodegenerative disorders.

In addition to its potential clinical applications, the ADRB2 is also a valuable biomarker for the diagnosis and progression of various diseases. For example, the ADRB2 has been used as a biomarker for heart failure, and is thought to be involved in the regulation of this condition. It has also been used as a biomarker for neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease.

The ADRB2 is a complex protein that is involved in the regulation of various physiological processes throughout the body. It is a potential drug target and has been identified as a biomarker for various diseases. Further research is needed to fully understand the role of the ADRB2 in the regulation of cardiovascular, respiratory, and neurochemical responses to the body's environment.

Protein Name: Adrenoceptor Beta 2

Functions: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine

The "ADRB2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ADRB2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets