Target Name: DACT2
NCBI ID: G168002
Review Report on DACT2 Target / Biomarker Content of Review Report on DACT2 Target / Biomarker
DACT2
Other Name(s): Dishevelled binding antagonist of beta catenin 2, transcript variant 1 | C6orf116 | dishevelled binding antagonist of beta catenin 2 | Dishevelled binding antagonist of beta catenin 2, transcript variant 3 | DAPPER2 | BA503C24.7 | DACT2 variant 3 | Dapper antagonist of catenin 2 | DACT2 variant 1 | Dapper homolog 2, antagonist of beta-catenin | dapper antagonist of catenin 2 | RP11-503C24.7 | dapper, antagonist of beta-catenin, homolog 2 | MGC133141 | DACT2_HUMAN | DPR2 | Dapper homolog 2 (isoform a) | OTTHUMP00000017658 | dapper homolog 2, antagonist of beta-catenin | Dapper 2 | Dapper homolog 2 (isoform c) | MGC133142 | Dapper homolog 2 | FLJ31232 | bA503C24.7

DACT2: A Promising Drug Target / Biomarker

DACT2 is a protein that is expressed in various tissues throughout the body, including the brain, heart, lungs, and gastrointestinal tract. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Despite its importance, little is known about DACT2. There are only a few studies that have explored its role in disease, and these studies have produced conflicting results. The lack of clear understanding of DACT2's function has hindered its potential as a drug target or biomarker.

However, recent studies have shed some light on the potential functions of DACT2. These studies have identified several potential targets for DACT2, including the production of neurotransmitters, the regulation of cellular signaling pathways, and the modulation of gene expression.

One potential function of DACT2 is its role in the production of neurotransmitters, such as dopamine and serotonin. These neurotransmitters are important for a variety of physiological processes, including mood regulation, appetite, and pain perception. DACT2 has been shown to play a role in the production of these neurotransmitters, and may be a potential target for drugs that target this pathway.

Another potential function of DACT2 is its role in regulating cellular signaling pathways. DACT2 has been shown to interact with a variety of signaling pathways, including TGF-β, NF-kappa-B, and PI3K. These signaling pathways are involved in a wide range of cellular processes, including cell growth, differentiation, and inflammation. By modulating these signaling pathways, DACT2 may play a role in the development and progression of a variety of diseases.

In addition to its potential role in neurotransmitter regulation, DACT2 has also been shown to modulate gene expression. DACT2 has been shown to interact with a variety of transcription factors, including SVN2, KLF1, and NF-kappa-B. These transcription factors are responsible for regulating the expression of genes, and DACT2 may play a role in modulating the activity of these transcription factors. This modulation of gene expression could have important implications for the development and progression of diseases.

Conclusion

DACT2 is a protein that has been shown to play a role in a variety of physiological processes throughout the body. While much is still known about its function, recent studies have identified several potential targets for DACT2, including its role in the production of neurotransmitters, its regulation of cellular signaling pathways, and its modulation of gene expression. These studies suggest that DACT2 may be a promising drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role and potential functions.

Protein Name: Dishevelled Binding Antagonist Of Beta Catenin 2

Functions: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity)

The "DACT2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DACT2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DACT3 | DACT3-AS1 | DAD1 | DAG1 | DAGLA | DAGLB | DALRD3 | DANCR | DAND5 | DANT2 | DAO | DAOA | DAOA-AS1 | DAP | DAP3 | DAPK1 | DAPK1-IT1 | DAPK2 | DAPK3 | DAPL1 | DAPP1 | DARS1 | DARS1-AS1 | DARS2 | DAW1 | DAXX | DAZ1 | DAZ2 | DAZ3 | DAZ4 | DAZAP1 | DAZAP2 | DAZAP2P1 | DAZL | DBET | DBF4 | DBF4B | DBF4P1 | DBH | DBH-AS1 | DBI | DBIL5P | DBIL5P2 | DBIP2 | DBIRD complex | DBN1 | DBNDD1 | DBNDD2 | DBNL | DBP | DBR1 | DBT | DBX1 | DBX2 | DCAF1 | DCAF10 | DCAF11 | DCAF12 | DCAF12L1 | DCAF12L2 | DCAF13 | DCAF13P3 | DCAF15 | DCAF16 | DCAF17 | DCAF4 | DCAF4L1 | DCAF4L2 | DCAF5 | DCAF6 | DCAF7 | DCAF8 | DCAF8L1 | DCAF8L2 | DCAKD | DCANP1 | DCBLD1 | DCBLD2 | DCC | DCD | DCDC1 | DCDC2 | DCDC2B | DCDC2C | DCHS1 | DCHS2 | DCK | DCLK1 | DCLK2 | DCLK3 | DCLRE1A | DCLRE1B | DCLRE1C | DCN | DCP1A | DCP1B | DCP2 | DCPS | DCST1 | DCST1-AS1