ACTL10: A Potential Drug Target and Biomarker (G170487)

Target Name: ACTL10

NCBI ID: G170487

ACTL10

ACTL10: A Potential Drug Target and Biomarker

ACTL10 is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the actinin family, which is known for their role in cell signaling and cytoskeletal organization. While the exact function of ACTL10 is not yet fully understood, research has suggested that it may be involved in a variety of physiological processes, including cell adhesion, migration, and survival.

Drug Target Potential

The potential drug target for ACTL10 is based on its involvement in cell signaling and the known functions of its family members. One of the key features of ACTL10 is its ability to interact with several different signaling pathways, including the TGF-β pathway and the PI3K/Akt pathway. These signaling pathways are involved in a wide range of cellular processes, including cell growth, differentiation, and survival. Therefore, targeting ACTL10 may be a promising strategy for the development of new pharmaceuticals for a variety of diseases.

Biomarker Potential

In addition to its potential as a drug target, ACTL10 may also be a useful biomarker for the diagnosis and monitoring of certain diseases. For example, research has suggested that ACTL10 may be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, ACTL10 has been shown to be expressed in a variety of cancer types, which may make it a useful biomarker for the detection and treatment of cancer.

Expression and Localization

The expression of ACTL10 is well established in a wide range of tissues and cells. Several studies have shown that ACTL10 is expressed in a variety of tissues, including the brain, heart, lungs, and gastrointestinal tract. In addition, research has suggested that ACTL10 is expressed in the primary cilium, which is the structure that forms the base of the microtubules in eukaryotic cells.

Function and Interaction

While the exact function of ACTL10 is not yet fully understood, research has suggested that it may be involved in a wide range of cellular processes. One of the key functions of ACTL10 is its ability to interact with several different signaling pathways, including the TGF-β pathway and the PI3K/Akt pathway. These signaling pathways are involved in a wide range of cellular processes, including cell growth, differentiation, and survival.

In addition to its role in signaling pathways, ACTL10 may also be involved in the regulation of cellular processes such as cell adhesion, migration, and survival. Several studies have shown that ACTL10 plays a role in the regulation of cell adhesion, by interacting with the protein PDZ1. Additionally, research has suggested that ACTL10 may be involved in the regulation of cell migration, by interacting with the protein NF-kappa-B1.

Conclusion

In conclusion, ACTL10 is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. Its function and interaction with signaling pathways and biomarkers make it a promising target for the development of new pharmaceuticals for a variety of diseases. Further research is needed to fully understand the role of ACTL10 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Actin Like 10

The "ACTL10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ACTL10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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