Target Name: LIPH
NCBI ID: G200879
Review Report on LIPH Target / Biomarker Content of Review Report on LIPH Target / Biomarker
LIPH
Other Name(s): phospholipase A(1) | ARWH2 | Lipase member H | HYPT7 | membrane-bound phosphatidic acid-selective phospholipase A1 | LPDLR | Lipase H | Membrane-associated phosphatidic acid-selective phospholipase A1-alpha | Phospholipase A1 member B | lipase, member H | PLA1B | LIPH_HUMAN | mPA-PLA1 alpha | LAH2 | LPD lipase-related protein | membrane-associated phosphatidic acid-selective phospholipase A1-alpha | AH | phospholipase A1 member B | Membrane-bound phosphatidic acid-selective phospholipase A1 | mPA-PLA1 | lipase H

Understanding The Role of LIPH in The Cell

Lipophosphorylase (LIPH) is a protein that is expressed in various cell types, including tissues, organs, and organs. It is a member of the phospholipase A (PLA) family, which is a group of enzymes that are involved in the breakdown of phospholipids. This family of enzymes is important for the functions of many different cell types, including the regulation of cell signaling pathways, the development and maintenance of cell structure, and the production of various signaling molecules.

One of the functions of LIPH is its role in the breakdown of phospholipids, which are a type of lipid molecule that is made up of two fatty acids linked together. These molecules are important for many different functions in the cell, including the formation of cell membranes, the storage of energy in the form of lipids, and the regulation of various signaling pathways. LIPH is involved in the breakdown of these phospholipids, which allows the cell to remove the phospholipids that are no longer needed and replace them with new ones.

Another function of LIPH is its role in the regulation of various signaling pathways. Many different signaling pathways rely on the breakdown of phospholipids, and LIPH is involved in the regulation of these pathways. For example, LIPH is involved in the regulation of the signal transduction pathway, which is the process by which a signal is transmitted from the cell membrane to the inside of the cell. This pathway is important for many different functions in the cell, including the regulation of cell growth, the development and maintenance of cell structure, and the production of various signaling molecules.

In addition to its role in the regulation of signaling pathways, LIPH is also involved in the production of various signaling molecules. Many signaling molecules, including proteins that are involved in cell signaling, are produced by the breakdown of phospholipids. LIPH is involved in the production of these signaling molecules, which allows it to play a role in the regulation of various cellular processes.

Despite its importance for many different functions in the cell, LIPH is not yet widely studied. There are many different techniques that can be used to study the behavior of LIPH, including biochemical assays, biophysical studies, and cell-based assays. In addition, there is a growing interest in developing new drugs that target LIPH, with the goal of using these drugs to treat various diseases.

One potential drug that targets LIPH is a protein called monoclonal antibody 2 (mAb2). MAb2 is a type of antibody that is designed to selectively bind to LIPH, and it has been shown to be effective in a variety of cellular assays. For example, mAb2 has been shown to be able to inhibit the activity of LIPH, which suggests that it could be a useful drug target for the treatment of various diseases.

Another potential drug that targets LIPH is a small molecule called 1,2-dimethylpropionitrile (DMP). DMP is a compound that is able to inhibit the activity of LIPH, and it has been shown to be effective in a variety of cellular assays. It is possible that DMP could be a useful drug for the treatment of various diseases, although more research is needed to determine its effectiveness.

In conclusion, LIPH is a protein that is involved in the breakdown of phospholipids, which are a type of lipid molecule that is important for many different functions in the cell. It is a member of the PLA family of enzymes, and it is involved in the regulation of various signaling pathways and the production of various signaling molecules. While more research is needed to fully understand the role of LIPH in the cell, it is clear that it is an important player in many different cellular processes. Additionally, new drugs that target LIPH are being developed to treat various diseases, and further studies are needed to determine their effectiveness.

Protein Name: Lipase H

Functions: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG)

The "LIPH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LIPH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LIPI | LIPJ | LIPK | LIPM | LIPN | Lipoxygenase | Liprin-beta-1-like | LIPT1 | LIPT2 | LIPT2-AS1 | LITAF | Liver Bile Transporters (LBAT) | LIX1 | LIX1-AS1 | LIX1L | LKAAEAR1 | LKB1-LIP1-SMAD4 complex | LL22NC03-63E9.3 | LLCFC1 | LLGL1 | LLGL2 | LLPH | LMAN1 | LMAN1L | LMAN2 | LMAN2L | LMBR1 | LMBR1L | LMBRD1 | LMBRD2 | LMCD1 | LMCD1-AS1 | LMF1 | LMF2 | LMLN | LMNA | LMNB1 | LMNB2 | LMNTD1 | LMNTD2 | LMNTD2-AS1 | LMO1 | LMO2 | LMO3 | LMO4 | LMO7 | LMO7-AS1 | LMO7DN | LMOD1 | LMOD2 | LMOD3 | LMTK2 | LMTK3 | LMX1A | LMX1B | LMX1B-DT | LNC-LBCS | LNCAROD | LNCARSR | LNCATV | LNCNEF | LNCOC1 | LNCOG | LNCPRESS1 | LNCRI | LNCRNA-ATB | LNCRNA-IUR | LNCTAM34A | LNP1 | LNPEP | LNPK | LNX1 | LNX1-AS1 | LNX2 | LOC100127946 | LOC100127955 | LOC100128002 | LOC100128028 | LOC100128050 | LOC100128059 | LOC100128079 | LOC100128093 | LOC100128164 | LOC100128242 | LOC100128288 | LOC100128317 | LOC100128361 | LOC100128398 | LOC100128494 | LOC100128593 | LOC100128770 | LOC100128966 | LOC100128988 | LOC100129034 | LOC100129098 | LOC100129148 | LOC100129175 | LOC100129203 | LOC100129215 | LOC100129316