MUC20 Plays A Role in Immune Response and Inflammation (G200958)
MUC20 Plays A Role in Immune Response and Inflammation
MUC20 (KIAA1359) is a protein that is expressed in various tissues throughout the body, including the lungs, heart, kidneys, and intestines. It is a member of the major histocompatibility complex (MHC) class I molecules, which are responsible for presenting antigens from the body's external environment, such as viruses and bacteria, to the immune system. MUC20 is also known as CD8+ T cell costimulatory molecule 20, and it has been shown to play a role in the regulation of immune responses and inflammation.
MUC20 is a 21-kDa protein that is expressed in various tissues throughout the body, including the lungs, heart, kidneys, and intestines. It is a member of the major histocompatibility complex (MHC) class I molecules, which are responsible for presenting antigens from the body's external environment, such as viruses and bacteria, to the immune system. MUC20 is also known as CD8+ T cell costimulatory molecule 20, and it has been shown to play a role in the regulation of immune responses and inflammation.
One of the functions of MUC20 is to facilitate the interaction between T cells and dendritic cells. T cells are a type of immune cell that play a critical role in the regulation of immune responses and inflammation. Dendritic cells are a type of immune cell that are responsible for presenting antigens from the body's external environment to T cells. MUC20 has been shown to interact with dendritic cells and to regulate the movement of T cells towards the site of an antigen presentation.
Another function of MUC20 is to regulate the production of immune cells by T cells. T cells are a type of immune cell that play a critical role in the regulation of immune responses and inflammation. MUC20 has been shown to interact with T cells and to regulate the production of T cells in the bone marrow.
MUC20 has also been shown to play a role in the regulation of inflammation. Inflammation is a critical response of the immune system to injury or infection. MUC20 has been shown to regulate the production of pro-inflammatory cytokines, such as interleukin-1 (IL-1), and to regulate the production of anti-inflammatory cytokines, such as IL-10.
MUC20 is also involved in the regulation of cell survival. Pro-inflammatory cytokines, such as IL-1, can cause damage to cells and contribute to the development of diseases such as cancer. MUC20 has been shown to play a role in the regulation of cell survival by preventing the production of pro-inflammatory cytokines.
MUC20 is also involved in the regulation of the immune response. MHC class I molecules present antigens from the body's external environment to T cells, and MUC20 has been shown to play a role in the regulation of T cell development and function.
MUC20 has also been shown to play a role in the regulation of the production of regulatory T cells. Regulatory T cells are a type of immune cell that help to maintain the balance of the immune system and play a critical role in the regulation of autoimmune diseases. MUC20 has been shown to play a role in the regulation of T cell development and function by regulating the production of regulatory T cells.
MUC20 has also been shown to play a role in the regulation of the production of natural killer cells. Natural killer cells are a type of immune cell that play a critical role in the regulation of immune responses and inflammation. MUC20 has been shown to play a role in the regulation of natural killer cell development and function by regulating the production of natural killer cells.
MUC20 is also involved in the regulation of the immune response by regulating the production of T follicular helper 1 (TFH1). TFH1 is a
Protein Name: Mucin 20, Cell Surface Associated
Functions: May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression
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More Common Targets
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