EPHX1: A Potential Drug Target and Biomarker (G2052)

Target Name: EPHX1

NCBI ID: G2052

EPHX1

EPHX1: A Potential Drug Target and Biomarker

Epoxide hydrolase 1 (ISOform A), also known as EPHX1, is a protein that is expressed in various cell types of the human body. It is a member of the superfamily of evolutionarily conserved enzymes known as the cytosolic hydrolases and is located in the endoplasmic reticulum. EPHX1 plays a crucial role in the regulation of cellular processes such as cell growth, apoptosis, and angiogenesis.

The research on EPHX1 has shown that it has a wide range of physiological functions. Firstly, it is involved in the regulation of cell growth and cell cycle progression. EPHX1 has been shown to play a negative role in cell proliferation and has been shown to promote the growth inhibition pathway in cancer cells. Secondly, EPHX1 is involved in the regulation of apoptosis. EPHX1 has been shown to play a crucial role in the regulation of apoptosis and has been shown to promote the apoptosis pathway in cancer cells. Thirdly, EPHX1 is involved in the regulation of angiogenesis. EPHX1 has been shown to play a crucial role in the regulation of angiogenesis and has been shown to promote the formation of new blood vessels in cancer.

Due to its various physiological functions, EPHX1 has been identified as a potential drug target and a biomarker. Studies have shown that inhibiting EPHX1 has potential therapeutic benefits in various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

One of the main targets of EPHX1 is the inhibition of its activity. various small molecules, including inhibitors, have been shown to inhibit EPHX1 activity and have been shown to have therapeutic benefits in various diseases. For example, inhibitors of EPHX1 have been shown to have potential therapeutic benefits in cancer, neurodegenerative diseases, and cardiovascular diseases.

Another approach to target EPHX1 is the use of antibodies. Monoclonal antibodies have been shown to be highly specific and sensitive, making them an attractive tool for targeting EPHX1. Monoclonal antibodies have been shown to be able to selectively bind to EPHX1 and to inhibit its activity, leading to the potential therapeutic benefits of targeting EPHX1.

In conclusion, EPHX1 is a protein that is involved in the regulation of various cellular processes in the human body. It has been shown to play a crucial role in the regulation of cell growth, apoptosis, and angiogenesis. The research on EPHX1 has shown that it has a wide range of physiological functions and has the potential to be a drug target and a biomarker. The inhibition of EPHX1 or the use of antibodies have been shown to have potential therapeutic benefits in various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Further research is needed to fully understand the role of EPHX1 and its potential as a drug target and biomarker.

Protein Name: Epoxide Hydrolase 1

Functions: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids (PubMed:22798687). Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol (PubMed:24958911)

The "EPHX1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EPHX1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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