ERP27: A Protein Potential as A Drug Target and Biomarker (G121506)

Target Name: ERP27

NCBI ID: G121506

ERP27

ERP27: A Protein Potential as A Drug Target and Biomarker

ERP27, also known as ERP27 variant 1, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ED family, which includes several similar proteins that play a crucial role in the regulation of cellular processes. One of the most interesting aspects of ERP27 is its potential as a drug target or biomarker.

The ERP27 protein is known for its role in the regulation of ion channels, which are responsible for the flow of electrical signals through cells. In addition, ERP27 has been shown to play a role in the regulation of gene expression, which is the process by which cells produce the proteins they need to perform their functions.

One of the most promising aspects of ERP27 is its potential as a drug target. Due to its role in the regulation of ion channels and gene expression, researchers believe that ERP27 could be a useful target for the development of new pharmaceuticals. For example, researchers have found that inhibiting the activity of ERP27 could be an effective way to treat certain neurological and cardiovascular conditions, such as Alzheimer's disease and heart failure.

In addition to its potential as a drug target, ERP27 also has the potential as a biomarker. Its expression has been shown to be elevated in a variety of diseases, including neurodegenerative disorders, cancer, and cardiovascular disease. This suggests that ERP27 could be a Useful biomarker for the diagnosis and treatment of these diseases.

Another promising aspect of ERP27 is its role in the regulation of cellular processes that are important for overall health and wellbeing. For example, research has shown that ERP27 plays a role in the regulation of blood pressure, which is critical for maintaining good cardiovascular health.

In conclusion, ERP27 is a protein that is expressed in various tissues of the body that is known for its role in the regulation of ion channels, gene expression, and cellular processes that are important for overall health and wellbeing. Its potential as a drug target and biomarker makes it an attractive target for research in the field of neurodegenerative disorders, cardiovascular disease, and other conditions that are associated with the regulation of ion channels and gene expression. Further research is needed to fully understand the role of ERP27 in these processes and to develop new treatments based on its potential as a drug target and biomarker.

Protein Name: Endoplasmic Reticulum Protein 27

Functions: Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates (PubMed:16940051, PubMed:23192347). Binds protein substrates via a hydrophobic pocket in the C-terminal domain (PubMed:16940051, PubMed:23192347). May play a role in the unfolded stress response (PubMed:23192347)

The "ERP27 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ERP27 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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