ERCC6L: A Potential Drug Target and Biomarker (G54821)

Target Name: ERCC6L

NCBI ID: G54821

ERCC6L

ERCC6L: A Potential Drug Target and Biomarker

ERCC6L, also known as protamineurea, is a protein that is expressed in the brain and is involved in the production of ammonia, which is a toxic compound that can cause a range of health problems, including brain damage. The research on ERCC6L has led to its potential as a drug target and biomarker.

The Role of ERCC6L in Ammonia Production

Ammonia is a colorless, odorless, and tasteless gas that is highly toxic to the nervous system and can cause a range of health problems, including:

* Nausea
* Vomiting
* Loss of consciousness
* Seizures
* Stupor
* coma

The production of ammonia is a complex process that involves multiple enzymes, including the enzyme ERCC6L. This protein is responsible for the production of ammonia from the amino acid L-aspartate.

ERCC6L: The Enzyme Responsible for Ammonia Production

ERCC6L is an enzyme that is expressed in the brain and is involved in the production of ammonia from L-aspartate. It is a critical enzyme in the production of ammonia, which is a toxic compound that can cause a range of health problems.

The production of ammonia from L-aspartate is a complex process that involves multiple enzymes, including ERCC6L. ERCC6L is the enzyme that is responsible for the production of ammonia from L-aspartate.

ERCC6L: Potential Drug Target

The potential drug target for ERCC6L is its role in the production of ammonia, which is a toxic compound that can cause a range of health problems. Researchers are exploring the use of drugs that can inhibit the activity of ERCC6L to treat conditions that are caused by high levels of ammonia, such as:

* neurodegenerative disorders
* Traumatic brain injury
* Seizures
* Stupor

ERCC6L: A Potential Biomarker

The research on ERCC6L has also led to its potential as a biomarker. The production of ammonia is a complex process that involves multiple enzymes, including ERCC6L. Therefore, the level of ammonia in the brain can be used as a biomarker for certain conditions.

Research has shown that high levels of ammonia can be associated with a range of health problems, including:

* Neurodegenerative disorders
* Traumatic brain injury
* Seizures
* Stupor

ERCC6L: Conclusion

ERCC6L is a protein that is involved in the production of ammonia from L-aspartate. The potential drug target for ERCC6L is its role in the production of ammonia, which is a toxic compound that can cause a range of health problems. The research on ERCC6L has also led to its potential as a biomarker for certain conditions. Further research is needed to fully understand the role of ERCC6L in ammonia production and its potential as a drug target and biomarker.

Protein Name: ERCC Excision Repair 6 Like, Spindle Assembly Checkpoint Helicase

Functions: DNA helicase that acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase (PubMed:17218258, PubMed:23973328). Functions as ATP-dependent DNA translocase (PubMed:23973328, PubMed:28977671). Can promote Holliday junction branch migration (in vitro) (PubMed:23973328)

The "ERCC6L Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ERCC6L comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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