ERVK13-1: A Drug Target / Disease Biomarker (G100507321)

Target Name: ERVK13-1

NCBI ID: G100507321

ERVK13-1

Other Name(s): Endogenous retrovirus group K13 member 1

ERVK13-1: A Drug Target / Disease Biomarker

ERVK13-1 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Endoplasmic Reticulum-Protein-Tubulin complex (ERPT), which is responsible for the transport of tubulin protein from the endoplasmic reticulum to various organelles, including the microtubules of the mitotic spindle.

ERVK13-1 has been identified as a potential drug target due to its involvement in various cellular processes that are important for the development and progression of various diseases, including cancer. Its expression has also been associated with the regulation of cellular processes that are important for the maintenance of tissue homeostasis, such as cell division, migration, and angiogenesis.

One of the key functions of ERVK13-1 is its role in the regulation of microtubule dynamics. Microtubules are important for the transport of various cellular organelles, including mitotic spindles, which are required for cell division and are involved in the regulation of various cellular processes that are important for the development and progression of cancer. The dynamics of microtubules can be regulated by various factors, including the level of tubulin protein, which is a key component of microtubules.

ERVK13-1 has been shown to play a role in the regulation of tubulin protein levels in various tissues. For example, studies have shown that ERVK13-1 can bind to tubulin protein and prevent its phosphorylation, which is a critical step in the regulation of tubulin protein levels. This function of ERVK13-1 suggests that it may be a useful target for drugs that are designed to inhibit tubulin protein phosphorylation and thereby inhibit microtubule dynamics.

In addition to its role in microtubule dynamics, ERVK13-1 has also been shown to be involved in the regulation of various cellular processes that are important for the maintenance of tissue homeostasis. For example, studies have shown that ERVK13-1 can regulate the migration of cells, which is an important process for the development and progression of cancer. Additionally, ERVK13-1 has been shown to play a role in the regulation of cell division, which is important for the growth and development of tissues and is critical for the development and progression of cancer.

ERVK13-1 has also been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. This process is important for the development and progression of cancer, as well as the regulation of tissue repair and regeneration.

Given its involvement in various cellular processes that are important for the development and progression of cancer, ERVK13-1 is a promising target for drugs that are designed to inhibit its function. Studies have shown that inhibiting ERVK13-1 function with small molecules or antibodies has the potential to inhibit the growth and spread of various cancer types, including breast, lung, and colorectal cancer.

In conclusion, ERVK13-1 is a protein that is involved in various cellular processes that are important for the development and progression of cancer. Its expression has also been associated with the regulation of cellular processes that are important for the maintenance of tissue homeostasis. As a result, ERVK13-1 is a promising target for drugs that are designed to inhibit its function. Further research is needed to fully understand the role of ERVK13-1 in the development and progression of cancer and to identify effective strategies for its inhibition.

Protein Name: Endogenous Retrovirus Group K13 Member 1

Functions: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution (By similarity)

The "ERVK13-1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ERVK13-1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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