Target Name: F8
NCBI ID: G2157
Review Report on F8 Target / Biomarker Content of Review Report on F8 Target / Biomarker
F8
Other Name(s): Coagulation factor VIII (isoform a) | Coagulation factor VIIIa | F8C | THPH13 | AHF | Antihemophilic factor | F8 variant 1 | antihemophilic factor | FVIIIa | coagulation factor VIII, procoagulant component | HEMA | Procoagulant component | Coagulation factor VIII, transcript variant 1 | coagulation factor VIII C2 domain | Factor VIIIa heavy chain, 92 kDa isoform | coagulation factor VIIIc | Factor VIIIa light chain | F8B | Factor VIII B chain | factor VIII F8B | Coagulation factor VIII | DXS1253E | coagulation factor VIII A1 domain | Factor VIIIa heavy chain, 200 kDa isoform | coagulation factor VIII | FVIII | Factor VIII F8B | FA8_HUMAN

Unlocking the Potential of F8 (Coagulation Factor VIII (ISO Form A)): A Drug Target and Biomarker

F8 (Coagulation factor VIII (ISO Form A)) is a critical protein involved in the blood clotting process. It is one of the eight proteins known as the coagulation factors, which are essential for blood clotting and maintaining tissue integrity. F8 plays a crucial role in the formation of stable blood clots, which are essential for delivering oxygen and nutrients to the body's tissues and for removing waste products.

Recent studies have identified F8 as a potential drug target and biomarker for various diseases, including cancer, cardiovascular diseases, and neurological disorders. In this article, we will explore the recent research on F8 and its potential as a drug target and biomarker.

F8 as a Drug Target

F8 has been identified as a potential drug target due to its involvement in various cellular processes that are crucial for cancer progression. F8 plays a role in the regulation of cell proliferation, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels). These processes are critical for cancer growth and progression.

Studies have shown that inhibiting F8 activity can lead to the inhibition of cancer cell growth and the regression of cancer tumors. Additionally, F8 has been shown to play a negative role in the development of cancer stem cells. This suggests that targeting F8 may be an effective way to treat cancer.

F8 as a Biomarker

F8 has also been identified as a potential biomarker for various diseases, including cancer, cardiovascular diseases, and neurological disorders. F8 levels have been shown to be elevated in various diseases, including cancer, cardiovascular diseases, and neurological disorders.

Studies have shown that F8 levels can be used as a diagnostic marker for various diseases, including cancer and cardiovascular diseases. For example, a study conducted by the American Heart Association found that F8 levels were significantly elevated in patients with cardiovascular disease compared to healthy individuals. This suggests that F8 may be a useful biomarker for the diagnosis and monitoring of cardiovascular diseases.

F8 as a Therapeutic Target

In addition to its potential as a drug target and biomarker, F8 has also been shown to be a therapeutic target for various diseases. F8 has been shown to play a role in the regulation of platelet function, which is crucial for blood clotting.

Studies have shown that inhibiting F8 activity can lead to the inhibition of blood clotting, which can be a therapeutic approach for treating bleeding disorders and other cardiovascular diseases. Additionally, F8 has been shown to play a role in the regulation of inflammation, which can be a therapeutic approach for treating various inflammatory diseases.

Conclusion

In conclusion, F8 (Coagulation factor VIII (ISO Form A)) is a critical protein involved in the blood clotting process. Its recent research as a drug target and biomarker suggests that targeting F8 may be an effective way to treat various diseases, including cancer, cardiovascular diseases, and neurological disorders. Further research is needed to fully understand the role of F8 as a therapeutic target and biomarker.

Protein Name: Coagulation Factor VIII

Functions: Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa

The "F8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about F8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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