SAMD4A: A Potential Drug Target and Biomarker (G23034)

Target Name: SAMD4A

NCBI ID: G23034

SAMD4A

SAMD4A: A Potential Drug Target and Biomarker

Introduction

SAMD4A (Sterile alpha motif domain containing 4A) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. It is a key regulator of gene expression in many cell types, including cancer cells. SAMD4A has been shown to play a role in the regulation of cell adhesion, migration, and invasion, which are important processes in the development and progression of many diseases, including cancer.

The SAMD4A gene

SAMD4A is a member of the SAMD4A gene family, which is characterized by the presence of a sterile alpha motif (SAM) in the protein coding region. The SAM is a specific DNA-binding motif that is often found in gene promoters, and it is known to play a role in the regulation of gene expression. The SAMD4A gene is located on chromosome 16, at position 186.2 and has a gene length of 1,894 base pairs.

The protein encoded by the SAMD4A gene

The protein encoded by the SAMD4A gene is a 21-kDa protein that is expressed in many different tissues and cell types. It is highly conserved, with a calculated pI of 4.8 and a predicted localization in the cytoplasm. The protein has been shown to have a number of different functions, including:

* Regulating cell adhesion: SAMD4A has been shown to play a role in regulating cell adhesion by preventing cell-cell interactions that could lead to the formation of tight junctions and adherens junctions, which are important for maintaining tissue structure and function.
* Promoting cell migration: SAMD4A has been shown to promote cell migration by regulating the activity of the protein actin, which is involved in the regulation of cell mechanics and is a key factor in the development of cancer.
* Involving in the regulation of cell invasion: SAMD4A has been shown to be involved in the regulation of cell invasion by the protein integrin, which is involved in the regulation of cell adhesion and migration.

The potential drug target

SAMD4A has been shown to be a potential drug target by its involvement in the regulation of cell adhesion, migration, and invasion. Many studies have suggested that inhibiting the activity of SAMD4A could be a useful strategy for the treatment of various diseases, including cancer. For example, studies have shown that inhibiting the activity of SAMD4A has been shown to inhibit the growth of cancer cells in cell culture and in animal models of cancer.

In addition, SAMD4A has also been shown to play a role in the regulation of stem cell self-renewal and proliferation, which could be a potential target for the treatment of diseases that are characterized by the over-production of stem cells.

The potential biomarker

SAMD4A has also been shown to be a potential biomarker for a number of diseases, including cancer. Its involvement in the regulation of cell adhesion, migration, and invasion makes it a potentially useful biomarker for the diagnosis and treatment of cancer. For example, studies have shown that the expression of SAMD4A is often increased in cancer cells, and that inhibiting its activity has been shown to be effective in inhibiting the growth of these cells.

In addition, the levels of SAMD4A have also been shown to be increased in the blood and other tissues of people with certain types of cancer, which could be used as a potential biomarker for the diagnosis of these diseases

Protein Name: Sterile Alpha Motif Domain Containing 4A

Functions: Acts as a translational repressor of SRE-containing messengers

The "SAMD4A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SAMD4A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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