Target Name: SAMD9
NCBI ID: G54809
Review Report on SAMD9 Target / Biomarker Content of Review Report on SAMD9 Target / Biomarker
SAMD9
Other Name(s): Sterile alpha motif domain-containing protein 9 | NFTC | sterile alpha motif domain containing 9 | SAM domain-containing protein 9 | DRIF1 | SAMD9_HUMAN | SAMD9 variant 1 | C7orf5 | MIRAGE | M7MLS2 | Sterile alpha motif domain containing 9, transcript variant 2 | Sterile alpha motif domain containing 9, transcript variant 1 | Expressed in aggressive fibromatosis | expressed in aggressive fibromatosis | OEF2 | OEF1 | KIAA2004 | SAMD9 variant 2 | FLJ20073

SAMD9: A Potential Drug Target and Biomarker

SAMD9, short for SARM-box RNA-binding protein 9, is a protein that is expressed in various tissues and cells throughout the body. It is a non-coding RNA-binding protein that has been shown to play a role in various cellular processes, including cell signaling, transcriptional regulation, and immune response.

One of the unique features of SAMD9 is its ability to interact with specific RNA molecules. This interaction allows SAMD9 to regulate the activity of other proteins and influence the expression of certain genes. This interaction between SAMD9 and RNA molecules makes it an attractive target for drug development.

SAMD9 has been shown to play a role in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that high levels of SAMD9 expression are associated with poor prognosis in patients with pancreatic cancer. Additionally, SAMD9 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential role in disease, SAMD9 has also been shown to be a valuable biomarker for certain diseases. For example, studies have shown that reducing SAMD9 expression can significantly reduce the severity of symptoms in patients with Alzheimer's disease. Additionally, SAMD9 has been shown to be a useful biomarker for tracking the effectiveness of certain treatments in patients with neurodegenerative diseases.

Despite the potential benefits of SAMD9 as a drug target and biomarker, much more research is needed to fully understand its role in these processes. Currently, there are limited studies that have focused specifically on the use of SAMD9 as a drug target or biomarker.

In conclusion, SAMD9 is a protein that has the potential to be a drug target and biomarker. Its ability to interact with specific RNA molecules and its association with various diseases make it an attractive target for further research. As research continues to develop, it is likely that we will learn more about the role of SAMD9 in these processes and how it can be used to treat a variety of diseases.

Protein Name: Sterile Alpha Motif Domain Containing 9

Functions: Double-stranded nucleic acid binding that acts as a an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules (PubMed:25428864, PubMed:28157624). May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion

The "SAMD9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SAMD9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SAMD9L | SAMHD1 | SAMM50 | SAMMSON | SAMSN1 | SAMSN1-AS1 | SANBR | SAP130 | SAP18 | SAP30 | SAP30-DT | SAP30BP | SAP30L | SAP30L-AS1 | SAPCD1 | SAPCD1-AS1 | SAPCD2 | SAR1A | SAR1B | SARAF | SARDH | SARM1 | SARNP | SARS1 | SARS2 | SART1 | SART3 | SASH1 | SASH3 | SASS6 | SAT1 | SAT1-DT | SAT2 | SATB1 | SATB1-AS1 | SATB2 | SATB2-AS1 | SATL1 | SAV1 | SAXO1 | SAXO2 | SAYSD1 | SBDS | SBDSP1 | SBF1 | SBF1P1 | SBF2 | SBF2-AS1 | SBK1 | SBK2 | SBK3 | SBNO1 | SBNO2 | SBSN | SBSPON | SC5D | SCAANT1 | SCAF1 | SCAF11 | SCAF4 | SCAF8 | SCAI | SCAMP1 | SCAMP1-AS1 | SCAMP2 | SCAMP3 | SCAMP4 | SCAMP5 | SCAND1 | SCAND2P | SCAND3 | SCAP | SCAPER | SCARA3 | SCARA5 | SCARB1 | SCARB2 | SCARF1 | SCARF2 | SCARNA1 | SCARNA10 | SCARNA11 | SCARNA12 | SCARNA13 | SCARNA14 | SCARNA15 | SCARNA16 | SCARNA17 | SCARNA18 | SCARNA2 | SCARNA20 | SCARNA21 | SCARNA22 | SCARNA23 | SCARNA27 | SCARNA28 | SCARNA3 | SCARNA4 | SCARNA5 | SCARNA6