FOSL2: A Protein Regulator of Cell Growth, Differentiation and Survival

Target Name: FOSL2

NCBI ID: G2355

FOSL2

FOSL2: A Protein Regulator of Cell Growth, Differentiation and Survival

FOSL2 (FOSL2_HUMAN), also known as FOS-L2, is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and kidneys. It is a key regulator of cell growth, differentiation, and survival , and is involved in many important cellular processes that are necessary for human health and development.

FOSL2 is a member of the FOS family of proteins, which are known for their ability to regulate cell growth and differentiation. The FOS family of proteins are named after Dr. fosmid, a jellyfish that was first identified by researchers as a key regulator of cell growth and differentiation.

FOSL2 is a 21-kDa protein that is expressed in a variety of tissues in the human body, including the brain, heart, liver, and kidneys. It is primarily localized to the cytoplasm of cells, where it plays a role in regulating the growth and differentiation of various cell types.

One of the key functions of FOSL2 is its ability to regulate cell proliferation. FOSL2 is known to be involved in the G1/S transition, which is the process by which cells prepare for cell division. During the G1 phase, FOSL2 helps to ensure that cells have enough copies of their genetic material and that all necessary proteins and organelles are present before the cell enters the S phase, where cell division takes place.

Another important function of FOSL2 is its role in cell survival. FOSL2 is known to be involved in the regulation of apoptosis, which is the process by which cells die when they have reached their lifespan or when they are no longer needed. FOSL2 helps to ensure that cells are able to commit suicide when they are no longer needed, which is important for maintaining the health and function of tissues.

FOSL2 is also involved in the regulation of cell migration. FOSL2 helps to ensure that cells are able to move and migrate to new locations in the body, where they can perform their necessary functions. This is important for the development and maintenance of tissues and organs , as well as for the proper functioning of the immune system.

In addition to its role in cell proliferation, apoptosis, and migration, FOSL2 is also involved in the regulation of many other cellular processes that are important for human health and development. For example, FOSL2 is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. FOSL2 also plays a role in the regulation of cell signaling, which is the process by which cells communicate with one another and coordinate their activities.

FOSL2 is also involved in the regulation of inflammation. FOSL2 is known to be involved in the regulation of the immune response, and is thought to play a role in the regulation of inflammatory responses. This is important for maintaining the health and function of tissues and organs, as well as for preventing the development of diseases such as cancer.

FOSL2 is also a potential drug target. Researchers have identified several potential drug targets for FOSL2, including the regulation of cell proliferation, apoptosis, migration, and inflammation. These drug targets are thought to be important for the development of new treatments for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In conclusion, FOSL2 is a key protein that is involved in a variety of important cellular processes that are necessary for human health and development. Its regulation of cell proliferation, apoptosis, migration, and inflammation makes it an attractive target for the development of new treatments for a variety of diseases. Further research is needed to fully understand the functions of FOSL2 and its potential as a drug target.

Protein Name: FOS Like 2, AP-1 Transcription Factor Subunit

Functions: Controls osteoclast survival and size (By similarity). As a dimer with JUN, activates LIF transcription (By similarity). Activates CEBPB transcription in PGE2-activated osteoblasts (By similarity)

The "FOSL2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FOSL2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets